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Antiviral activity of Cenostigma pluviosum var. peltophoroides extract and fractions against SARS-CoV-2.
Pattaro-Júnior JR, Araújo IG, Moraes CB, Barbosa CG, Philippsen GS, Freitas-Junior LH, Guidi AC, de Mello JCP, Peralta RM, Fernandez MA, Teixeira RR, Seixas FAV. Pattaro-Júnior JR, et al. Among authors: freitas junior lh. J Biomol Struct Dyn. 2023 Sep-Oct;41(15):7297-7308. doi: 10.1080/07391102.2022.2120078. Epub 2022 Sep 7. J Biomol Struct Dyn. 2023. PMID: 36069130
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.
Pandey RP, Nascimento MS, Franco CH, Bortoluci K, Silva MN, Zingales B, Gibaldi D, Castaño Barrios L, Lannes-Vieira J, Cariste LM, Vasconcelos JR, Moraes CB, Freitas-Junior LH, Kalil J, Alcântara L, Cunha-Neto E. Pandey RP, et al. Among authors: freitas junior lh. Antimicrob Agents Chemother. 2022 Nov 15;66(11):e0028422. doi: 10.1128/aac.00284-22. Epub 2022 Oct 31. Antimicrob Agents Chemother. 2022. PMID: 36314800 Free PMC article.
Potential of plant extracts in targeting SARS-CoV-2 main protease: an in vitro and in silico study.
de Araujo IG, Pattaro-Júnior JR, Barbosa CG, Philippsen GS, Silva AR, Ioshino RS, Moraes CB, Freitas-Junior LH, Barros L, Peralta RM, Fernandez MA, Seixas FAV. de Araujo IG, et al. Among authors: freitas junior lh. J Biomol Struct Dyn. 2023;41(21):12204-12213. doi: 10.1080/07391102.2023.2166589. Epub 2023 Jan 18. J Biomol Struct Dyn. 2023. PMID: 36651196
A potential antiviral against COVID-19 obtained from Byrsonima coccolobifolia leaves extract.
Rodrigues CM, Bento CC, Moraes CB, Gomes C, Ioshino RS, Freitas-Junior LH, de Castro Spadari C, Ishida K, Vilegas W, Carvalho JCS, Ferreira MJP, Carbone V, Piacente S, Molina de Angelo R, Honorio KM, Sannomiya M. Rodrigues CM, et al. Among authors: freitas junior lh. Fitoterapia. 2024 Mar;173:105820. doi: 10.1016/j.fitote.2024.105820. Epub 2024 Jan 9. Fitoterapia. 2024. PMID: 38211642
Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra).
Barros ALAN, Silva VC, Ribeiro-Junior AF, Cardoso MG, Costa SR, Moraes CB, Barbosa CG, Coleone AP, Simões RP, Cabral WF, Falcão RM, Vasconcelos AG, Rocha JA, Arcanjo DDR, Batagin-Neto A, Borges TKS, Gonçalves J, Brand GD, Freitas-Junior LHG, Eaton P, Marani M, Kato MJ, Plácido A, Leite JRSA. Barros ALAN, et al. Among authors: freitas junior lhg. Pharmaceutics. 2024 Jan 29;16(2):190. doi: 10.3390/pharmaceutics16020190. Pharmaceutics. 2024. PMID: 38399250 Free PMC article.
SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies.
Cioffi VB, de Castro-Amarante MF, Lulla A, Andreata-Santos R, Cruz MC, Moreno ACR, de Oliveira Silva M, de Miranda Peres B, de Freitas Junior LHG, Moraes CB, Durigon EL, Gordon NC, Hyvönen M, de Souza Ferreira LC, Balan A. Cioffi VB, et al. Among authors: de freitas junior lhg. Sci Rep. 2023 Oct 5;13(1):16821. doi: 10.1038/s41598-023-43720-8. Sci Rep. 2023. PMID: 37798298 Free PMC article.
The evaluation of in vitro antichagasic and anti-SARS-CoV-2 potential of inclusion complexes of β- and methyl-β-cyclodextrin with naphthoquinone.
Oliveira VDS, Silva CC, de Freitas Oliveira JW, da Silva MS, Ferreira PG, da Siva FC, Ferreira VF, Barbosa EG, Barbosa CG, Moraes CB, Freitas-Junior LHG, Converti A, Lima ÁAN. Oliveira VDS, et al. Among authors: freitas junior lhg. J Drug Deliv Sci Technol. 2023 Mar;81:104229. doi: 10.1016/j.jddst.2023.104229. Epub 2023 Feb 8. J Drug Deliv Sci Technol. 2023. PMID: 36776572 Free PMC article.
Nano-multilamellar lipid vesicles promote the induction of SARS-CoV-2 immune responses by a protein-based vaccine formulation.
Rodrigues-Jesus MJ, Teixeira de Pinho Favaro M, Venceslau-Carvalho AA, de Castro-Amarante MF, da Silva Almeida B, de Oliveira Silva M, Andreata-Santos R, Gomes Barbosa C, Brito SCM, Freitas-Junior LH, Boscardin SB, de Souza Ferreira LC. Rodrigues-Jesus MJ, et al. Among authors: freitas junior lh. Nanomedicine. 2022 Sep;45:102595. doi: 10.1016/j.nano.2022.102595. Epub 2022 Aug 27. Nanomedicine. 2022. PMID: 36031045 Free PMC article.
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors.
Freire MCLC, Noske GD, Bitencourt NV, Sanches PRS, Santos-Filho NA, Gawriljuk VO, de Souza EP, Nogueira VHR, de Godoy MO, Nakamura AM, Fernandes RS, Godoy AS, Juliano MA, Peres BM, Barbosa CG, Moraes CB, Freitas-Junior LHG, Cilli EM, Guido RVC, Oliva G. Freire MCLC, et al. Among authors: freitas junior lhg. Molecules. 2021 Aug 12;26(16):4896. doi: 10.3390/molecules26164896. Molecules. 2021. PMID: 34443484 Free PMC article.
69 results