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Serodiagnosis of canine leishmaniasis using a novel recombinant chimeric protein constructed with distinct B-cell epitopes from antigenic Leishmania infantum proteins.
Vale DL, Lage DP, Machado AS, Freitas CS, de Oliveira D, Galvani NC, Fernandes BB, Luiz GP, Oliveira JS, Oliveira-da-Silva JA, Ramos FF, Santos TTO, Siqueira WF, Alves LA, Chávez-Fumagalli MA, de Magalhães-Soares DF, Silveira JAG, Bueno LL, Fujiwara RT, Machado-de-Ávila RA, Martins VT, Coelho EAF. Vale DL, et al. Among authors: freitas cs. Vet Parasitol. 2021 Aug;296:109513. doi: 10.1016/j.vetpar.2021.109513. Epub 2021 Jul 1. Vet Parasitol. 2021. PMID: 34225189
Comorbidity associated to Ascaris suum infection during pulmonary fibrosis exacerbates chronic lung and liver inflammation and dysfunction but not affect the parasite cycle in mice.
Oliveira FMS, da Paixão Matias PH, Kraemer L, Gazzinelli-Guimarães AC, Santos FV, Amorim CCO, Nogueira DS, Freitas CS, Caliari MV, Bartholomeu DC, Bueno LL, Russo RC, Fujiwara RT. Oliveira FMS, et al. Among authors: freitas cs. PLoS Negl Trop Dis. 2019 Nov 25;13(11):e0007896. doi: 10.1371/journal.pntd.0007896. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31765381 Free PMC article.
A clioquinol-containing Pluronic® F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model.
Tavares GSV, Mendonça DVC, Pereira IAG, Oliveira-da-Silva JA, Ramos FF, Lage DP, Machado AS, Carvalho LM, Reis TAR, Perin L, Carvalho AMRS, Ottoni FM, Ludolf F, Freitas CS, Bandeira RS, Silva AM, Chávez-Fumagalli MA, Duarte MC, Menezes-Souza D, Alves RJ, Roatt BM, Coelho EAF. Tavares GSV, et al. Among authors: freitas cs. Parasite. 2020;27:29. doi: 10.1051/parasite/2020027. Epub 2020 Apr 30. Parasite. 2020. PMID: 32351209 Free PMC article.
Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis.
Lage DP, Ribeiro PAF, Dias DS, Mendonça DVC, Ramos FF, Carvalho LM, Steiner BT, Tavares GSV, Martins VT, Machado AS, Oliveira-da-Silva JA, Santos TTO, Freitas CS, Oliveira JS, Roatt BM, Machado-de-Ávila RA, Humbert MV, Christodoulides M, Coelho EAF. Lage DP, et al. Among authors: freitas cs. Vaccines (Basel). 2020 Jun 9;8(2):289. doi: 10.3390/vaccines8020289. Vaccines (Basel). 2020. PMID: 32526867 Free PMC article.
A Leishmania amastigote-specific hypothetical protein evaluated as recombinant protein plus Th1 adjuvant or DNA plasmid-based vaccine to protect against visceral leishmaniasis.
Oliveira-da-Silva JA, Machado AS, Ramos FF, Tavares GSV, Lage DP, Mendonça DVC, Pereira IAG, Santos TTO, Martins VT, Carvalho LM, Freitas CS, Ludolf F, Reis TAR, Bandeira RS, Silva AM, Costa LE, Oliveira JS, Duarte MC, Roatt BM, Teixeira AL, Coelho EAF. Oliveira-da-Silva JA, et al. Among authors: freitas cs. Cell Immunol. 2020 Oct;356:104194. doi: 10.1016/j.cellimm.2020.104194. Epub 2020 Aug 13. Cell Immunol. 2020. PMID: 32827943
Corrigendum to "Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis". Molecular Immunology 124 (2020) 161-171.
Oliveira-da-Silva JA, Lage DP, Ramos FF, Machado AS, Tavares GSV, Mendonça DVC, Pereira IAG, Martins VT, Carvalho LM, Ludolf F, Santos TTO, Reis TAR, Freitas CS, Bandeira RS, Silva AM, Costa LE, Oliveira JS, Duarte MC, Roatt BM, Teixeira AL, Coelho EAF. Oliveira-da-Silva JA, et al. Among authors: freitas cs. Mol Immunol. 2020 Dec;128:55. doi: 10.1016/j.molimm.2020.09.002. Epub 2020 Oct 15. Mol Immunol. 2020. PMID: 33068834 No abstract available.
Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
Freitas CS, Oliveira-da-Silva JA, Lage DP, Costa RR, Mendonça DVC, Martins VT, Reis TAR, Antinarelli LMR, Machado AS, Tavares GSV, Ramos FF, Coelho VTS, Brito RCF, Ludolf F, Chávez-Fumagalli MA, Roatt BM, Ramos GS, Munkert J, Ottoni FM, Campana PRV, Humbert MV, Coimbra ES, Braga FC, Pádua RM, Coelho EAF. Freitas CS, et al. Parasitol Res. 2021 Jan;120(1):321-335. doi: 10.1007/s00436-020-06971-2. Epub 2020 Nov 16. Parasitol Res. 2021. PMID: 33191446 Free PMC article.
Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis.
Reis TAR, Oliveira-da-Silva JA, Tavares GSV, Mendonça DVC, Freitas CS, Costa RR, Lage DP, Martins VT, Machado AS, Ramos FF, Silva AM, Ludolf F, Antinarelli LMR, Brito RCF, Chávez-Fumagalli MA, Humbert MV, Roatt BM, Coimbra ES, Coelho EAF. Reis TAR, et al. Among authors: freitas cs. Exp Parasitol. 2021 Feb;221:108059. doi: 10.1016/j.exppara.2020.108059. Epub 2020 Dec 16. Exp Parasitol. 2021. PMID: 33338468
Leishmania eukaryotic elongation Factor-1 beta protein is immunogenic and induces parasitological protection in mice against Leishmania infantum infection.
Santos TTO, Machado AS, Ramos FF, Oliveira-da-Silva JA, Lage DP, Tavares GSV, Mendonça DVC, Cardoso MS, Siqueira WF, Martins VT, Ludolf F, Reis TAR, Carvalho LM, Freitas CS, Bandeira RS, Silva AM, Oliveira JS, Moreira RLF, Fujiwara RT, Roatt BM, Chávez-Fumagalli MA, Humbert MV, Teixeira AL, Coelho EAF. Santos TTO, et al. Among authors: freitas cs. Microb Pathog. 2021 Feb;151:104745. doi: 10.1016/j.micpath.2021.104745. Epub 2021 Jan 21. Microb Pathog. 2021. PMID: 33485994
In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis.
Freitas CS, Lage DP, Oliveira-da-Silva JA, Costa RR, Mendonça DVC, Martins VT, Reis TAR, Antinarelli LMR, Machado AS, Tavares GSV, Ramos FF, Brito RCF, Ludolf F, Chávez-Fumagalli MA, Roatt BM, Ramos GS, Munkert J, Ottoni FM, Campana PRV, Duarte MC, Gonçalves DU, Coimbra ES, Braga FC, Pádua RM, Coelho EAF. Freitas CS, et al. Parasite. 2021;28:38. doi: 10.1051/parasite/2021036. Epub 2021 Apr 14. Parasite. 2021. PMID: 33851916 Free PMC article.
150 results