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Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca2+ entry after pressure-overload induced cardiac remodelling.
Camacho Londoño JE, Kuryshev V, Zorn M, Saar K, Tian Q, Hübner N, Nawroth P, Dietrich A, Birnbaumer L, Lipp P, Dieterich C, Freichel M. Camacho Londoño JE, et al. Among authors: freichel m. Prog Biophys Mol Biol. 2021 Jan;159:86-104. doi: 10.1016/j.pbiomolbio.2020.07.006. Epub 2020 Jul 29. Prog Biophys Mol Biol. 2021. PMID: 32738354
TRPC3 channels are required for synaptic transmission and motor coordination.
Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. Hartmann J, et al. Among authors: freichel m. Neuron. 2008 Aug 14;59(3):392-8. doi: 10.1016/j.neuron.2008.06.009. Neuron. 2008. PMID: 18701065 Free PMC article.
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
Klaiber M, Kruse M, Völker K, Schröter J, Feil R, Freichel M, Gerling A, Feil S, Dietrich A, Londoño JE, Baba HA, Abramowitz J, Birnbaumer L, Penninger JM, Pongs O, Kuhn M. Klaiber M, et al. Among authors: freichel m. Basic Res Cardiol. 2010 Sep;105(5):583-95. doi: 10.1007/s00395-010-0098-z. Epub 2010 Mar 30. Basic Res Cardiol. 2010. PMID: 20352235 Free PMC article.
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Mathar I, Vennekens R, Meissner M, Kees F, Van der Mieren G, Camacho Londoño JE, Uhl S, Voets T, Hummel B, van den Bergh A, Herijgers P, Nilius B, Flockerzi V, Schweda F, Freichel M. Mathar I, et al. Among authors: freichel m. J Clin Invest. 2010 Sep;120(9):3267-79. doi: 10.1172/JCI41348. Epub 2010 Aug 2. J Clin Invest. 2010. PMID: 20679729 Free PMC article.
Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F. Phelan KD, et al. Among authors: freichel m. Mol Pharmacol. 2012 Mar;81(3):384-92. doi: 10.1124/mol.111.075341. Epub 2011 Dec 5. Mol Pharmacol. 2012. PMID: 22144671 Free PMC article.
146 results