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Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies.
Chucair-Elliott AJ, Ocanas SR, Stanford DR, Hadad N, Wronowski B, Otalora L, Stout MB, Freeman WM. Chucair-Elliott AJ, et al. Among authors: freeman wm. Geroscience. 2019 Oct;41(5):691-708. doi: 10.1007/s11357-019-00090-2. Epub 2019 Sep 7. Geroscience. 2019. PMID: 31493147 Free PMC article.
Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia.
Chucair-Elliott AJ, Ocañas SR, Stanford DR, Ansere VA, Buettner KB, Porter H, Eliason NL, Reid JJ, Sharpe AL, Stout MB, Beckstead MJ, Miller BF, Richardson A, Freeman WM. Chucair-Elliott AJ, et al. Among authors: freeman wm. Commun Biol. 2020 Nov 19;3(1):693. doi: 10.1038/s42003-020-01418-x. Commun Biol. 2020. PMID: 33214681 Free PMC article.
Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex.
Ocañas SR, Ansere VA, Tooley KB, Hadad N, Chucair-Elliott AJ, Stanford DR, Rice S, Wronowski B, Pham KD, Hoffman JM, Austad SN, Stout MB, Freeman WM. Ocañas SR, et al. Among authors: freeman wm. Mol Neurobiol. 2022 Aug;59(8):4669-4702. doi: 10.1007/s12035-022-02860-0. Epub 2022 May 20. Mol Neurobiol. 2022. PMID: 35589920 Free PMC article.
Translatomic response of retinal Müller glia to acute and chronic stress.
Chucair-Elliott AJ, Ocañas SR, Pham K, Van Der Veldt M, Cheyney A, Stanford D, Gurley J, Elliott MH, Freeman WM. Chucair-Elliott AJ, et al. Among authors: freeman wm. Neurobiol Dis. 2022 Dec;175:105931. doi: 10.1016/j.nbd.2022.105931. Epub 2022 Nov 22. Neurobiol Dis. 2022. PMID: 36423879 Free PMC article.
Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley K, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Jun 2:2023.03.07.531435. doi: 10.1101/2023.03.07.531435. bioRxiv. 2023. PMID: 36945372 Free PMC article. Updated. Preprint.
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Jun 1:2023.03.07.531562. doi: 10.1101/2023.03.07.531562. bioRxiv. 2023. PMID: 36945656 Free PMC article. Updated. Preprint.
Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley KB, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. Geroscience. 2023 Oct;45(5):3019-3043. doi: 10.1007/s11357-023-00859-6. Epub 2023 Jul 1. Geroscience. 2023. PMID: 37393197 Free PMC article.
166 results