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Enterohepatic Shunt-Driven Cholemia Predisposes to Liver Cancer.
Yeoh BS, Saha P, Golonka RM, Zou J, Petrick JL, Abokor AA, Xiao X, Bovilla VR, Bretin ACA, Rivera-Esteban J, Parisi D, Florio AA, Weinstein SJ, Albanes D, Freeman GJ, Gohara AF, Ciudin A, Pericàs JM, Joe B, Schwabe RF, McGlynn KA, Gewirtz AT, Vijay-Kumar M. Yeoh BS, et al. Among authors: freeman gj. Gastroenterology. 2022 Dec;163(6):1658-1671.e16. doi: 10.1053/j.gastro.2022.08.033. Epub 2022 Aug 18. Gastroenterology. 2022. PMID: 35988658 Free PMC article.
Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD-L1) expression in colorectal carcinoma.
Ugai T, Shimizu T, Kawamura H, Ugai S, Takashima Y, Usui G, Väyrynen JP, Okadome K, Haruki K, Akimoto N, Masugi Y, da Silva A, Mima K, Zhang X, Chan AT, Wang M, Garrett WS, Freeman GJ, Meyerhardt JA, Nowak JA, Song M, Giannakis M, Ogino S. Ugai T, et al. Among authors: freeman gj. Clin Transl Immunology. 2023 Aug 2;12(8):e1453. doi: 10.1002/cti2.1453. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37538192 Free PMC article.
Regulation of HHLA2 expression in kidney cancer and myeloid cells.
Shigemura T, Perrot N, Huang Z, Bhatt RS, Sheshdeh AB, Ahmar NE, Ghandour F, Signoretti S, McDermott DF, Freeman GJ, Mahoney KM. Shigemura T, et al. Among authors: freeman gj. BMC Cancer. 2023 Oct 27;23(1):1039. doi: 10.1186/s12885-023-11496-9. BMC Cancer. 2023. PMID: 37891555 Free PMC article.
An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy.
Cowles SC, Sheen A, Santollani L, Lutz EA, Lax BM, Palmeri JR, Freeman GJ, Wittrup KD. Cowles SC, et al. Among authors: freeman gj. MAbs. 2022 Jan-Dec;14(1):2088454. doi: 10.1080/19420862.2022.2088454. MAbs. 2022. PMID: 35924382 Free PMC article.
Preclinical models for development of immune-oncology therapies.
Wang Y, Shelton SE, Kastrunes G, Barbie DA, Freeman GJ, Marasco WA. Wang Y, et al. Among authors: freeman gj. Immuno-oncol Insights. 2022;3(8):379-398. doi: 10.18609/ioi.2022.41. Epub 2022 Sep 26. Immuno-oncol Insights. 2022. PMID: 37132013 Free PMC article.
Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects.
Wang Y, Buck A, Piel B, Zerefa L, Murugan N, Coherd CD, Miklosi AG, Johal H, Bastos RN, Huang K, Ficial M, Laimon YN, Signoretti S, Zhong Z, Hoang SM, Kastrunes GM, Grimaud M, Fayed A, Yuan HC, Nguyen QD, Thai T, Ivanova EV, Paweletz CP, Wu MR, Choueiri TK, Wee JO, Freeman GJ, Barbie DA, Marasco WA. Wang Y, et al. Among authors: freeman gj. Mol Cancer. 2024 Mar 16;23(1):56. doi: 10.1186/s12943-024-01952-w. Mol Cancer. 2024. PMID: 38491381 Free PMC article.
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy.
Yu H, Liu J, Bu X, Ma Z, Yao Y, Li J, Zhang T, Song W, Xiao X, Sun Y, Xiong W, Shi J, Dai P, Xiang B, Duan H, Yan X, Wu F, Zhang WC, Lin D, Hu H, Zhang H, Slack FJ, He HH, Freeman GJ, Wei W, Zhang J. Yu H, et al. Among authors: freeman gj. Cell Chem Biol. 2024 Apr 18;31(4):776-791.e7. doi: 10.1016/j.chembiol.2023.09.001. Epub 2023 Sep 25. Cell Chem Biol. 2024. PMID: 37751743
Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.
Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA. Wang Y, et al. Among authors: freeman gj. iScience. 2024 Jan 15;27(2):108879. doi: 10.1016/j.isci.2024.108879. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327771 Free PMC article.
443 results