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Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator.
Bursavich MG, Harrison BA, Acharya R, Costa DE, Freeman EA, Hrdlicka LA, Jin H, Kapadnis S, Moffit JS, Murphy D, Nolan SJ, Patzke H, Tang C, Van Voorhies HE, Wen M, Koenig G, Blain JF, Burnett DA. Bursavich MG, et al. Among authors: freeman ea. J Med Chem. 2021 Oct 14;64(19):14426-14447. doi: 10.1021/acs.jmedchem.1c00904. Epub 2021 Sep 22. J Med Chem. 2021. PMID: 34550687
MEK1/2 activity modulates TREM2 cell surface recruitment.
Schapansky J, Grinberg YY, Osiecki DM, Freeman EA, Walker SG, Karran E, Gopalakrishnan SM, Talanian RV. Schapansky J, et al. Among authors: freeman ea. J Biol Chem. 2021 Jan-Jun;296:100218. doi: 10.1074/jbc.RA120.014352. Epub 2020 Dec 25. J Biol Chem. 2021. PMID: 33839686 Free PMC article.
From bench to board-side: Academic teaching careers.
Freeman EA, Theodosiou NA, Anderson WJ. Freeman EA, et al. Dev Biol. 2020 Mar 1;459(1):43-48. doi: 10.1016/j.ydbio.2019.10.032. Epub 2019 Nov 1. Dev Biol. 2020. PMID: 31682809 Free article.
36 results