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A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. Hayek SS, et al. Among authors: freedman bi. Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26. Nat Med. 2017. PMID: 28650456 Free PMC article.
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods.
Knowler WC, Coresh J, Elston RC, Freedman BI, Iyengar SK, Kimmel PL, Olson JM, Plaetke R, Sedor JR, Seldin MF; Family Investigation of Nephropathy and Diabetes Research Group. Knowler WC, et al. Among authors: freedman bi. J Diabetes Complications. 2005 Jan-Feb;19(1):1-9. doi: 10.1016/j.jdiacomp.2003.12.007. J Diabetes Complications. 2005. PMID: 15642484 Review.
Familial clustering of chronic kidney disease.
Satko SG, Sedor JR, Iyengar SK, Freedman BI. Satko SG, et al. Among authors: freedman bi. Semin Dial. 2007 May-Jun;20(3):229-36. doi: 10.1111/j.1525-139X.2007.00282.x. Semin Dial. 2007. PMID: 17555489 Review.
MYH9 is associated with nondiabetic end-stage renal disease in African Americans.
Kao WH, Klag MJ, Meoni LA, Reich D, Berthier-Schaad Y, Li M, Coresh J, Patterson N, Tandon A, Powe NR, Fink NE, Sadler JH, Weir MR, Abboud HE, Adler SG, Divers J, Iyengar SK, Freedman BI, Kimmel PL, Knowler WC, Kohn OF, Kramp K, Leehey DJ, Nicholas SB, Pahl MV, Schelling JR, Sedor JR, Thornley-Brown D, Winkler CA, Smith MW, Parekh RS; Family Investigation of Nephropathy and Diabetes Research Group. Kao WH, et al. Among authors: freedman bi. Nat Genet. 2008 Oct;40(10):1185-92. doi: 10.1038/ng.232. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794854 Free PMC article.
MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.
Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, Bowden DW, Oleksyk T, McKenzie LM, Kajiyama H, Ahuja TS, Berns JS, Briggs W, Cho ME, Dart RA, Kimmel PL, Korbet SM, Michel DM, Mokrzycki MH, Schelling JR, Simon E, Trachtman H, Vlahov D, Winkler CA. Kopp JB, et al. Among authors: freedman bi. Nat Genet. 2008 Oct;40(10):1175-84. doi: 10.1038/ng.226. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794856 Free PMC article.
The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.
Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcón GS, Brown EE, McGwin G Jr, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Langefeld CD, Kimberly RP; PROFILE Study Group. Freedman BI, et al. Am J Nephrol. 2010;32(1):66-72. doi: 10.1159/000314688. Epub 2010 Jun 7. Am J Nephrol. 2010. PMID: 20523037 Free PMC article.
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