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Structural, functional, and immunogenicity implications of F9 gene recoding.
Katneni UK, Alexaki A, Hunt RC, Hamasaki-Katagiri N, Hettiarachchi GK, Kames JM, McGill JR, Holcomb DD, Athey JC, Lin B, Parunov LA, Kafri T, Lu Q, Peters R, Ovanesov MV, Freedberg DI, Bar H, Komar AA, Sauna ZE, Kimchi-Sarfaty C. Katneni UK, et al. Among authors: freedberg di. Blood Adv. 2022 Jul 12;6(13):3932-3944. doi: 10.1182/bloodadvances.2022007094. Blood Adv. 2022. PMID: 35413099 Free PMC article.
Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B.
Simhadri VL, Hamasaki-Katagiri N, Lin BC, Hunt R, Jha S, Tseng SC, Wu A, Bentley AA, Zichel R, Lu Q, Zhu L, Freedberg DI, Monroe DM, Sauna ZE, Peters R, Komar AA, Kimchi-Sarfaty C. Simhadri VL, et al. Among authors: freedberg di. J Med Genet. 2017 May;54(5):338-345. doi: 10.1136/jmedgenet-2016-104072. Epub 2016 Dec 22. J Med Genet. 2017. PMID: 28007939 Free PMC article.
Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies.
Alexaki A, Hettiarachchi GK, Athey JC, Katneni UK, Simhadri V, Hamasaki-Katagiri N, Nanavaty P, Lin B, Takeda K, Freedberg D, Monroe D, McGill JR, Peters R, Kames JM, Holcomb DD, Hunt RC, Sauna ZE, Gelinas A, Janjic N, DiCuccio M, Bar H, Komar AA, Kimchi-Sarfaty C. Alexaki A, et al. Sci Rep. 2019 Oct 29;9(1):15449. doi: 10.1038/s41598-019-51984-2. Sci Rep. 2019. PMID: 31664102 Free PMC article.
Glycosylation States on Intact Proteins Determined by NMR Spectroscopy.
Hargett AA, Marcella AM, Yu H, Li C, Orwenyo J, Battistel MD, Wang LX, Freedberg DI. Hargett AA, et al. Among authors: freedberg di. Molecules. 2021 Jul 16;26(14):4308. doi: 10.3390/molecules26144308. Molecules. 2021. PMID: 34299586 Free PMC article.
60 results