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Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders.
Front Genome Ed. 2021 Jan 12;2:623717. doi: 10.3389/fgeed.2020.623717. eCollection 2020.
Front Genome Ed. 2021.
PMID: 34713244
Free PMC article.
Review.
Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene.
Frederiksen HR, Holst B, Ramakrishna S, Muddashetty R, Schmid B, Freude K.
Frederiksen HR, et al.
Stem Cell Res. 2019 Jan;34:101368. doi: 10.1016/j.scr.2018.101368. Epub 2018 Dec 24.
Stem Cell Res. 2019.
PMID: 30634129
Free article.
Item in Clipboard
Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.
Frederiksen HR, Holst B, Mau-Holzmann UA, Freude K, Schmid B.
Frederiksen HR, et al.
Stem Cell Res. 2019 Mar;35:101403. doi: 10.1016/j.scr.2019.101403. Epub 2019 Feb 7.
Stem Cell Res. 2019.
PMID: 30769329
Free article.
Item in Clipboard
Cell Type Specific Expression of Toll-Like Receptors in Human Brains and Implications in Alzheimer's Disease.
Frederiksen HR, Haukedal H, Freude K.
Frederiksen HR, et al.
Biomed Res Int. 2019 Jul 18;2019:7420189. doi: 10.1155/2019/7420189. eCollection 2019.
Biomed Res Int. 2019.
PMID: 31396533
Free PMC article.
Review.
Item in Clipboard
Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology.
Rivera-Sánchez P, Søndergaard L, Wathikthinnakon M, B D Magnusson H, Frederiksen HR, Aabæk Hammer F, Taleb R, Christian Cassidy C, Tranholm Bruun M, Tümer Z, Holst B, Brasch-Andersen C, Møller RS, Freude K, Chandrasekaran A.
Rivera-Sánchez P, et al. Among authors: frederiksen hr.
Stem Cell Res. 2023 Sep;71:103193. doi: 10.1016/j.scr.2023.103193. Epub 2023 Aug 25.
Stem Cell Res. 2023.
PMID: 37651830
Free article.
Item in Clipboard
The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes.
Calloe K, Geryk M, Freude K, Treat JA, Vold VA, Frederiksen HRS, Broendberg AK, Frederiksen TC, Jensen HK, Cordeiro JM.
Calloe K, et al. Among authors: frederiksen hrs.
Europace. 2022 Dec 9;24(12):2015-2027. doi: 10.1093/europace/euac090.
Europace. 2022.
PMID: 35726875
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Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing.
Mikkelsen RB, Frederiksen HRS, Gjerris M, Holst B, Hyttel P, Luo Y, Freude K, Sandøe P.
Mikkelsen RB, et al. Among authors: frederiksen hrs.
CRISPR J. 2019 Dec;2(6):362-369. doi: 10.1089/crispr.2019.0024.
CRISPR J. 2019.
PMID: 31860350
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