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Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
Kiryluk K, Li Y, Scolari F, Sanna-Cherchi S, Choi M, Verbitsky M, Fasel D, Lata S, Prakash S, Shapiro S, Fischman C, Snyder HJ, Appel G, Izzi C, Viola BF, Dallera N, Del Vecchio L, Barlassina C, Salvi E, Bertinetto FE, Amoroso A, Savoldi S, Rocchietti M, Amore A, Peruzzi L, Coppo R, Salvadori M, Ravani P, Magistroni R, Ghiggeri GM, Caridi G, Bodria M, Lugani F, Allegri L, Delsante M, Maiorana M, Magnano A, Frasca G, Boer E, Boscutti G, Ponticelli C, Mignani R, Marcantoni C, Di Landro D, Santoro D, Pani A, Polci R, Feriozzi S, Chicca S, Galliani M, Gigante M, Gesualdo L, Zamboli P, Battaglia GG, Garozzo M, Maixnerová D, Tesar V, Eitner F, Rauen T, Floege J, Kovacs T, Nagy J, Mucha K, Pączek L, Zaniew M, Mizerska-Wasiak M, Roszkowska-Blaim M, Pawlaczyk K, Gale D, Barratt J, Thibaudin L, Berthoux F, Canaud G, Boland A, Metzger M, Panzer U, Suzuki H, Goto S, Narita I, Caliskan Y, Xie J, Hou P, Chen N, Zhang H, Wyatt RJ, Novak J, Julian BA, Feehally J, Stengel B, Cusi D, Lifton RP, Gharavi AG. Kiryluk K, et al. Among authors: frasca g. Nat Genet. 2014 Nov;46(11):1187-96. doi: 10.1038/ng.3118. Epub 2014 Oct 12. Nat Genet. 2014. PMID: 25305756 Free PMC article.
Genome-wide association study identifies susceptibility loci for IgA nephropathy.
Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP. Gharavi AG, et al. Among authors: frasca g. Nat Genet. 2011 Mar 13;43(4):321-7. doi: 10.1038/ng.787. Nat Genet. 2011. PMID: 21399633 Free PMC article.
IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23.
Gharavi AG, Yan Y, Scolari F, Schena FP, Frasca GM, Ghiggeri GM, Cooper K, Amoroso A, Viola BF, Battini G, Caridi G, Canova C, Farhi A, Subramanian V, Nelson-Williams C, Woodford S, Julian BA, Wyatt RJ, Lifton RP. Gharavi AG, et al. Among authors: frasca gm. Nat Genet. 2000 Nov;26(3):354-7. doi: 10.1038/81677. Nat Genet. 2000. PMID: 11062479
Search for genetic association between IgA nephropathy and candidate genes selected by function or by gene mapping at loci IGAN2 and IGAN3.
Bertinetto FE, Calafell F, Roggero S, Chidichimo R, Garino E, Marcuccio C, Coppo R, Scolari F, Frascá GM, Savoldi S, Schena FP, Amoroso A; European IgA Nephropathy Consortium. Bertinetto FE, et al. Nephrol Dial Transplant. 2012 Jun;27(6):2328-37. doi: 10.1093/ndt/gfr633. Epub 2011 Nov 29. Nephrol Dial Transplant. 2012. PMID: 22131235
Genetic variant of C1GalT1 contributes to the susceptibility to IgA nephropathy.
Pirulli D, Crovella S, Ulivi S, Zadro C, Bertok S, Rendine S, Scolari F, Foramitti M, Ravani P, Roccatello D, Savoldi S, Cerullo G, Lanzilotta SG, Bisceglia L, Zelante L, Floege J, Alexopoulos E, Kirmizis D, Ghiggeri GM, Frascà G, Schena FP, Amoroso A; European IgAN Consortium. Pirulli D, et al. Among authors: frasca g. J Nephrol. 2009 Jan-Feb;22(1):152-9. J Nephrol. 2009. PMID: 19229831
The IgA nephropathy Biobank. An important starting point for the genetic dissection of a complex trait.
Schena FP, Cerullo G, Torres DD, Scolari F, Foramitti M, Amoroso A, Pirulli D, Floege J, Mertens PR, Zerres K, Alexopoulos E, Kirmizis D, Zelante L, Bisceglia L, Ghiggeri GM, Frascà GM; European IgA nephropathy Consortium. Schena FP, et al. Among authors: frasca gm. BMC Nephrol. 2005 Dec 5;6:14. doi: 10.1186/1471-2369-6-14. BMC Nephrol. 2005. PMID: 16329758 Free PMC article.
Cis and trans regulatory elements in NPHS2 promoter: implications in proteinuria and progression of renal diseases.
Di Duca M, Oleggini R, Sanna-Cherchi S, Pasquali L, Di Donato A, Parodi S, Bertelli R, Caridi G, Frasca G, Cerullo G, Amoroso A, Schena FP, Scolari F, Ghiggeri GM; European IgA Nephropathy Consortium. Di Duca M, et al. Among authors: frasca g. Kidney Int. 2006 Oct;70(7):1332-41. doi: 10.1038/sj.ki.5001767. Epub 2006 Aug 9. Kidney Int. 2006. PMID: 16900088 Free article.
252 results