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Page 1
Adhesion-mediated mechanosignaling forces mitohormesis.
Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM. Tharp KM, et al. Among authors: frankino pa. Cell Metab. 2021 Jul 6;33(7):1322-1341.e13. doi: 10.1016/j.cmet.2021.04.017. Epub 2021 May 20. Cell Metab. 2021. PMID: 34019840 Free PMC article.
A Futile Battle? Protein Quality Control and the Stress of Aging.
Higuchi-Sanabria R, Frankino PA, Paul JW 3rd, Tronnes SU, Dillin A. Higuchi-Sanabria R, et al. Among authors: frankino pa. Dev Cell. 2018 Jan 22;44(2):139-163. doi: 10.1016/j.devcel.2017.12.020. Dev Cell. 2018. PMID: 29401418 Free PMC article. Review.
Spatial regulation of the actin cytoskeleton by HSF-1 during aging.
Higuchi-Sanabria R, Paul JW 3rd, Durieux J, Benitez C, Frankino PA, Tronnes SU, Garcia G, Daniele JR, Monshietehadi S, Dillin A. Higuchi-Sanabria R, et al. Among authors: frankino pa. Mol Biol Cell. 2018 Oct 15;29(21):2522-2527. doi: 10.1091/mbc.E18-06-0362. Epub 2018 Aug 22. Mol Biol Cell. 2018. PMID: 30133343 Free PMC article.
Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization.
Moehle EA, Higuchi-Sanabria R, Tsui CK, Homentcovschi S, Tharp KM, Zhang H, Chi H, Joe L, de Los Rios Rogers M, Sahay A, Kelet N, Benitez C, Bar-Ziv R, Garcia G, Shen K, Frankino PA, Schinzel RT, Shalem O, Dillin A. Moehle EA, et al. Among authors: frankino pa. Sci Adv. 2021 Oct 29;7(44):eabj6818. doi: 10.1126/sciadv.abj6818. Epub 2021 Oct 29. Sci Adv. 2021. PMID: 34714674 Free PMC article.
UPRER promotes lipophagy independent of chaperones to extend life span.
Daniele JR, Higuchi-Sanabria R, Durieux J, Monshietehadi S, Ramachandran V, Tronnes SU, Kelet N, Sanchez M, Metcalf MG, Garcia G, Frankino PA, Benitez C, Zeng M, Esping DJ, Joe L, Dillin A. Daniele JR, et al. Among authors: frankino pa. Sci Adv. 2020 Jan 1;6(1):eaaz1441. doi: 10.1126/sciadv.aaz1441. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31911951 Free PMC article.
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER.
Schinzel RT, Higuchi-Sanabria R, Shalem O, Moehle EA, Webster BM, Joe L, Bar-Ziv R, Frankino PA, Durieux J, Pender C, Kelet N, Kumar SS, Savalia N, Chi H, Simic M, Nguyen NT, Dillin A. Schinzel RT, et al. Among authors: frankino pa. Cell. 2019 Nov 27;179(6):1306-1318.e18. doi: 10.1016/j.cell.2019.10.018. Epub 2019 Nov 21. Cell. 2019. PMID: 31761535 Free PMC article.
Measurements of Physiological Stress Responses in C. Elegans.
Bar-Ziv R, Frakes AE, Higuchi-Sanabria R, Bolas T, Frankino PA, Gildea HK, Metcalf MG, Dillin A. Bar-Ziv R, et al. Among authors: frankino pa. J Vis Exp. 2020 May 21;(159):10.3791/61001. doi: 10.3791/61001. J Vis Exp. 2020. PMID: 32510480 Free PMC article.
18 results