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Myeloid PHD2 deficiency accelerates neointima formation via Hif-1α.
Christoph M, Pfluecke C, Mensch M, Augstein A, Jellinghaus S, Ende G, Mierke J, Franke K, Wielockx B, Ibrahim K, Poitz DM. Christoph M, et al. Among authors: franke k. Mol Immunol. 2022 Sep;149:48-58. doi: 10.1016/j.molimm.2022.06.003. Epub 2022 Jun 17. Mol Immunol. 2022. PMID: 35724581
Hypoxia-mediated regulation of stem cell fate.
Singh RP, Franke K, Wielockx B. Singh RP, et al. Among authors: franke k. High Alt Med Biol. 2012 Sep;13(3):162-8. doi: 10.1089/ham.2012.1043. High Alt Med Biol. 2012. PMID: 22994515 Review.
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, Bergmann S, Breier G, Baretton G, Fong GH, Greaves DR, Bornstein S, Chavakis T, Fandrey J, Gassmann M, Wielockx B. Franke K, et al. Blood. 2013 Feb 21;121(8):1436-45. doi: 10.1182/blood-2012-08-449181. Epub 2012 Dec 20. Blood. 2013. PMID: 23264599 Free PMC article.
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Singh RP, Franke K, Kalucka J, Mamlouk S, Muschter A, Gembarska A, Grinenko T, Willam C, Naumann R, Anastassiadis K, Stewart AF, Bornstein S, Chavakis T, Breier G, Waskow C, Wielockx B. Singh RP, et al. Among authors: franke k. Blood. 2013 Jun 27;121(26):5158-66. doi: 10.1182/blood-2012-12-471185. Epub 2013 May 10. Blood. 2013. PMID: 23667053 Free article.
Erythrocytosis: the HIF pathway in control.
Franke K, Gassmann M, Wielockx B. Franke K, et al. Blood. 2013 Aug 15;122(7):1122-8. doi: 10.1182/blood-2013-01-478065. Epub 2013 Jun 3. Blood. 2013. PMID: 23733342 Free article. Review.
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.
Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J. Siegert I, et al. Among authors: franke k. Cell Rep. 2015 Dec 15;13(10):2048-55. doi: 10.1016/j.celrep.2015.11.005. Epub 2015 Nov 25. Cell Rep. 2015. PMID: 26628374 Free article.
646 results