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New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing.
Keller A, Graefen A, Ball M, Matzas M, Boisguerin V, Maixner F, Leidinger P, Backes C, Khairat R, Forster M, Stade B, Franke A, Mayer J, Spangler J, McLaughlin S, Shah M, Lee C, Harkins TT, Sartori A, Moreno-Estrada A, Henn B, Sikora M, Semino O, Chiaroni J, Rootsi S, Myres NM, Cabrera VM, Underhill PA, Bustamante CD, Vigl EE, Samadelli M, Cipollini G, Haas J, Katus H, O'Connor BD, Carlson MR, Meder B, Blin N, Meese E, Pusch CM, Zink A. Keller A, et al. Among authors: franke a. Nat Commun. 2012 Feb 28;3:698. doi: 10.1038/ncomms1701. Nat Commun. 2012. PMID: 22426219 Free article.
Genome-wide miRNA signatures of human longevity.
ElSharawy A, Keller A, Flachsbart F, Wendschlag A, Jacobs G, Kefer N, Brefort T, Leidinger P, Backes C, Meese E, Schreiber S, Rosenstiel P, Franke A, Nebel A. ElSharawy A, et al. Among authors: franke a. Aging Cell. 2012 Aug;11(4):607-16. doi: 10.1111/j.1474-9726.2012.00824.x. Epub 2012 May 30. Aging Cell. 2012. PMID: 22533606 Free article.
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software.
Forster M, Forster P, Elsharawy A, Hemmrich G, Kreck B, Wittig M, Thomsen I, Stade B, Barann M, Ellinghaus D, Petersen BS, May S, Melum E, Schilhabel MB, Keller A, Schreiber S, Rosenstiel P, Franke A. Forster M, et al. Among authors: franke a. Nucleic Acids Res. 2013 Jan 7;41(1):e16. doi: 10.1093/nar/gks836. Epub 2012 Sep 10. Nucleic Acids Res. 2013. PMID: 22965131 Free PMC article.
Paleoproteomic study of the Iceman's brain tissue.
Maixner F, Overath T, Linke D, Janko M, Guerriero G, van den Berg BH, Stade B, Leidinger P, Backes C, Jaremek M, Kneissl B, Meder B, Franke A, Egarter-Vigl E, Meese E, Schwarz A, Tholey A, Zink A, Keller A. Maixner F, et al. Among authors: franke a. Cell Mol Life Sci. 2013 Oct;70(19):3709-22. doi: 10.1007/s00018-013-1360-y. Epub 2013 Jun 6. Cell Mol Life Sci. 2013. PMID: 23739949
miRNAs can be generally associated with human pathologies as exemplified for miR-144.
Keller A, Leidinger P, Vogel B, Backes C, ElSharawy A, Galata V, Mueller SC, Marquart S, Schrauder MG, Strick R, Bauer A, Wischhusen J, Beier M, Kohlhaas J, Katus HA, Hoheisel J, Franke A, Meder B, Meese E. Keller A, et al. Among authors: franke a. BMC Med. 2014 Dec 3;12:224. doi: 10.1186/s12916-014-0224-0. BMC Med. 2014. PMID: 25465851 Free PMC article.
New insights into the genetics of glioblastoma multiforme by familial exome sequencing.
Backes C, Harz C, Fischer U, Schmitt J, Ludwig N, Petersen BS, Mueller SC, Kim YJ, Wolf NM, Katus HA, Meder B, Furtwängler R, Franke A, Bohle R, Henn W, Graf N, Keller A, Meese E. Backes C, et al. Among authors: franke a. Oncotarget. 2015 Mar 20;6(8):5918-31. doi: 10.18632/oncotarget.2950. Oncotarget. 2015. PMID: 25537509 Free PMC article.
1,697 results