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Sialoglycan binding triggers spike opening in a human coronavirus.
Pronker MF, Creutznacher R, Drulyte I, Hulswit RJG, Li Z, van Kuppeveld FJM, Snijder J, Lang Y, Bosch BJ, Boons GJ, Frank M, de Groot RJ, Hurdiss DL. Pronker MF, et al. Among authors: frank m. Nature. 2023 Dec;624(7990):201-206. doi: 10.1038/s41586-023-06599-z. Epub 2023 Oct 4. Nature. 2023. PMID: 37794193 Free PMC article.
The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron.
Toelzer C, Gupta K, Yadav SKN, Hodgson L, Williamson MK, Buzas D, Borucu U, Powers K, Stenner R, Vasileiou K, Garzoni F, Fitzgerald D, Payré C, Gautam G, Lambeau G, Davidson AD, Verkade P, Frank M, Berger I, Schaffitzel C. Toelzer C, et al. Among authors: frank m. Sci Adv. 2022 Nov 25;8(47):eadc9179. doi: 10.1126/sciadv.adc9179. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417532 Free PMC article.
GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery.
van Schie L, Van Breedam W, Roels C, Schepens B, Frank M, Mehdipour AR, Laukens B, Nerinckx W, Santens F, Devos S, Rossey I, Thooft K, Vanmarcke S, Van Hecke A, Saelens X, Callewaert N. van Schie L, et al. Among authors: frank m. MAbs. 2023 Jan-Dec;15(1):2210709. doi: 10.1080/19420862.2023.2210709. MAbs. 2023. PMID: 37211816 Free PMC article.
Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation.
Allen JD, Chawla H, Samsudin F, Zuzic L, Shivgan AT, Watanabe Y, He WT, Callaghan S, Song G, Yong P, Brouwer PJM, Song Y, Cai Y, Duyvesteyn HME, Malinauskas T, Kint J, Pino P, Wurm MJ, Frank M, Chen B, Stuart DI, Sanders RW, Andrabi R, Burton DR, Li S, Bond PJ, Crispin M. Allen JD, et al. Among authors: frank m. Biochemistry. 2021 Jul 13;60(27):2153-2169. doi: 10.1021/acs.biochem.1c00279. Epub 2021 Jul 2. Biochemistry. 2021. PMID: 34213308 Free PMC article.
Symbol Nomenclature for Graphical Representations of Glycans.
Varki A, Cummings RD, Aebi M, Packer NH, Seeberger PH, Esko JD, Stanley P, Hart G, Darvill A, Kinoshita T, Prestegard JJ, Schnaar RL, Freeze HH, Marth JD, Bertozzi CR, Etzler ME, Frank M, Vliegenthart JF, Lütteke T, Perez S, Bolton E, Rudd P, Paulson J, Kanehisa M, Toukach P, Aoki-Kinoshita KF, Dell A, Narimatsu H, York W, Taniguchi N, Kornfeld S. Varki A, et al. Among authors: frank m. Glycobiology. 2015 Dec;25(12):1323-4. doi: 10.1093/glycob/cwv091. Glycobiology. 2015. PMID: 26543186 Free PMC article. No abstract available.
3,582 results