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Symmetric activation and modulation of the human calcium-sensing receptor.
Park J, Zuo H, Frangaj A, Fu Z, Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ, Eng E, Lee Y, Kloss B, Liu Z, Hendrickson WA, Potter CS, Carragher B, Graziano J, Conigrave AD, Frank J, Clarke OB, Fan QR. Park J, et al. Among authors: frangaj a. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2115849118. doi: 10.1073/pnas.2115849118. Proc Natl Acad Sci U S A. 2021. PMID: 34916296 Free PMC article.
Structure of human GABAB receptor in an inactive state.
Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, Liu Z, Lin X, Williams JP, Rice WJ, Eng ET, Huang RK, Soni RK, Kloss B, Yu Z, Javitch JA, Hendrickson WA, Slesinger PA, Quick M, Graziano J, Yu H, Fiehn O, Clarke OB, Frank J, Fan QR. Park J, et al. Among authors: frangaj a. Nature. 2020 Aug;584(7820):304-309. doi: 10.1038/s41586-020-2452-0. Epub 2020 Jun 24. Nature. 2020. PMID: 32581365 Free PMC article.
Structural biology of GABAB receptor.
Frangaj A, Fan QR. Frangaj A, et al. Neuropharmacology. 2018 Jul 1;136(Pt A):68-79. doi: 10.1016/j.neuropharm.2017.10.011. Epub 2017 Oct 12. Neuropharmacology. 2018. PMID: 29031577 Free PMC article. Review.
Structural basis for auxiliary subunit KCTD16 regulation of the GABAB receptor.
Zuo H, Glaaser I, Zhao Y, Kurinov I, Mosyak L, Wang H, Liu J, Park J, Frangaj A, Sturchler E, Zhou M, McDonald P, Geng Y, Slesinger PA, Fan QR. Zuo H, et al. Among authors: frangaj a. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8370-8379. doi: 10.1073/pnas.1903024116. Epub 2019 Apr 10. Proc Natl Acad Sci U S A. 2019. PMID: 30971491 Free PMC article.
Author Correction: Structure of human GABAB receptor in an inactive state.
Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, Liu Z, Lin X, Williams JP, Rice WJ, Eng ET, Huang RK, Soni RK, Kloss B, Yu Z, Javitch JA, Hendrickson WA, Slesinger PA, Quick M, Graziano J, Yu H, Fiehn O, Clarke OB, Frank J, Fan QR. Park J, et al. Among authors: frangaj a. Nature. 2020 Jul;583(7818):E29. doi: 10.1038/s41586-020-2543-y. Nature. 2020. PMID: 32665714 Free PMC article.
Promiscuous G-protein activation by the calcium-sensing receptor.
Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu GB, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grassucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR. Zuo H, et al. Among authors: frangaj a. Nature. 2024 Apr 17. doi: 10.1038/s41586-024-07331-1. Online ahead of print. Nature. 2024. PMID: 38632411