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A simple linearization method unveils hidden enzymatic assay interferences.
Pinto MF, Ripoll-Rozada J, Ramos H, Watson EE, Franck C, Payne RJ, Saraiva L, Pereira PJB, Pastore A, Rocha F, Martins PM. Pinto MF, et al. Among authors: franck c. Biophys Chem. 2019 Sep;252:106193. doi: 10.1016/j.bpc.2019.106193. Epub 2019 May 29. Biophys Chem. 2019. PMID: 31195341
Rapid assembly and profiling of an anticoagulant sulfoprotein library.
Watson EE, Ripoll-Rozada J, Lee AC, Wu MCL, Franck C, Pasch T, Premdjee B, Sayers J, Pinto MF, Martins PM, Jackson SP, Pereira PJB, Payne RJ. Watson EE, et al. Among authors: franck c. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13873-13878. doi: 10.1073/pnas.1905177116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221752 Free PMC article.
CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation.
Zhong Y, Paudel BP, Ryan DP, Low JKK, Franck C, Patel K, Bedward MJ, Torrado M, Payne RJ, van Oijen AM, Mackay JP. Zhong Y, et al. Among authors: franck c. Nat Commun. 2020 Mar 23;11(1):1519. doi: 10.1038/s41467-020-15183-2. Nat Commun. 2020. PMID: 32251276 Free PMC article.
Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.
Norman A, Franck C, Christie M, Hawkins PME, Patel K, Ashhurst AS, Aggarwal A, Low JKK, Siddiquee R, Ashley CL, Steain M, Triccas JA, Turville S, Mackay JP, Passioura T, Payne RJ. Norman A, et al. Among authors: franck c. ACS Cent Sci. 2021 Jun 23;7(6):1001-1008. doi: 10.1021/acscentsci.0c01708. Epub 2021 May 27. ACS Cent Sci. 2021. PMID: 34230894 Free PMC article.
Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Bedding MJ, Franck C, Johansen-Leete J, Aggarwal A, Maxwell JWC, Patel K, Hawkins PME, Low JKK, Siddiquee R, Sani HM, Ford DJ, Turville S, Mackay JP, Passioura T, Christie M, Payne RJ. Bedding MJ, et al. Among authors: franck c. ACS Chem Biol. 2024 Jan 19;19(1):141-152. doi: 10.1021/acschembio.3c00568. Epub 2023 Dec 12. ACS Chem Biol. 2024. PMID: 38085789
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Patel K, Walport LJ, Walshe JL, Solomon PD, Low JKK, Tran DH, Mouradian KS, Silva APG, Wilkinson-White L, Norman A, Franck C, Matthews JM, Guss JM, Payne RJ, Passioura T, Suga H, Mackay JP. Patel K, et al. Among authors: franck c. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26728-26738. doi: 10.1073/pnas.2003086117. Epub 2020 Oct 12. Proc Natl Acad Sci U S A. 2020. PMID: 33046654 Free PMC article.
353 results