Francisco AF - Search Results

1

Biological factors that impinge on Chagas disease drug development.

Francisco AF, Jayawardhana S, Lewis MD, Taylor MC, Kelly JM. Francisco AF, et al. Parasitology. 2017 Dec;144(14):1871-1880. doi: 10.1017/S0031182017001469. Epub 2017 Aug 23. Parasitology. 2017. PMID: 28831944 Free PMC article. Review.

2

Trypanosoma cruzi: desferrioxamine decreases mortality and parasitemia in infected mice through a trypanostatic effect.

Arantes JM, Francisco AF, de Abreu Vieira PM, Silva M, Araújo MS, de Carvalho AT, Pedrosa ML, Carneiro CM, Tafuri WL, Martins-Filho OA, Elói-Santos SM. Arantes JM, et al. Among authors: francisco af. Exp Parasitol. 2011 Aug;128(4):401-8. doi: 10.1016/j.exppara.2011.05.011. Epub 2011 May 18. Exp Parasitol. 2011. PMID: 21620835

3

A new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging.

Lewis MD, Francisco AF, Taylor MC, Kelly JM. Lewis MD, et al. Among authors: francisco af. J Biomol Screen. 2015 Jan;20(1):36-43. doi: 10.1177/1087057114552623. Epub 2014 Oct 8. J Biomol Screen. 2015. PMID: 25296657 Free PMC article. Review.

4

Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.

Francisco AF, Lewis MD, Jayawardhana S, Taylor MC, Chatelain E, Kelly JM. Francisco AF, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4653-61. doi: 10.1128/AAC.00520-15. Epub 2015 May 26. Antimicrob Agents Chemother. 2015. PMID: 26014936 Free PMC article.

5

Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs".

Francisco AF, Lewis MD, Jayawardhana S, Taylor MC, Chatelain E, Kelly JM. Francisco AF, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7925. doi: 10.1128/AAC.02022-15. Antimicrob Agents Chemother. 2015. PMID: 26578702 Free PMC article. No abstract available.

6

Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.

Lewis MD, Francisco AF, Taylor MC, Jayawardhana S, Kelly JM. Lewis MD, et al. Among authors: francisco af. Cell Microbiol. 2016 Oct;18(10):1429-43. doi: 10.1111/cmi.12584. Epub 2016 May 25. Cell Microbiol. 2016. PMID: 26918803 Free PMC article.

7

Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.

Kishore KG, Ghashghaei O, Estarellas C, Mestre MM, Monturiol C, Kielland N, Kelly JM, Francisco AF, Jayawardhana S, Muñoz-Torrero D, Pérez B, Luque FJ, Gámez-Montaño R, Lavilla R. Kishore KG, et al. Among authors: francisco af. Angew Chem Int Ed Engl. 2016 Jul 25;55(31):8994-8. doi: 10.1002/anie.201604109. Epub 2016 Jun 17. Angew Chem Int Ed Engl. 2016. PMID: 27314630

8

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.

Francisco AF, Jayawardhana S, Lewis MD, White KL, Shackleford DM, Chen G, Saunders J, Osuna-Cabello M, Read KD, Charman SA, Chatelain E, Kelly JM. Francisco AF, et al. Sci Rep. 2016 Oct 17;6:35351. doi: 10.1038/srep35351. Sci Rep. 2016. PMID: 27748443 Free PMC article.

9

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.

Brand S, Ko EJ, Viayna E, Thompson S, Spinks D, Thomas M, Sandberg L, Francisco AF, Jayawardhana S, Smith VC, Jansen C, De Rycker M, Thomas J, MacLean L, Osuna-Cabello M, Riley J, Scullion P, Stojanovski L, Simeons FRC, Epemolu O, Shishikura Y, Crouch SD, Bakshi TS, Nixon CJ, Reid IH, Hill AP, Underwood TZ, Hindley SJ, Robinson SA, Kelly JM, Fiandor JM, Wyatt PG, Marco M, Miles TJ, Read KD, Gilbert IH. Brand S, et al. Among authors: francisco af. J Med Chem. 2017 Sep 14;60(17):7284-7299. doi: 10.1021/acs.jmedchem.7b00463. Epub 2017 Aug 27. J Med Chem. 2017. PMID: 28844141 Free PMC article.

10

Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.

Campos MC, Phelan J, Francisco AF, Taylor MC, Lewis MD, Pain A, Clark TG, Kelly JM. Campos MC, et al. Among authors: francisco af. Sci Rep. 2017 Oct 31;7(1):14407. doi: 10.1038/s41598-017-14986-6. Sci Rep. 2017. PMID: 29089615 Free PMC article.

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