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Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens.
Moutaftsi M, Tscharke DC, Vaughan K, Koelle DM, Stern L, Calvo-Calle M, Ennis F, Terajima M, Sutter G, Crotty S, Drexler I, Franchini G, Yewdell JW, Head SR, Blum J, Peters B, Sette A. Moutaftsi M, et al. Among authors: franchini g. Future Microbiol. 2010 Feb;5(2):221-39. doi: 10.2217/fmb.09.110. Future Microbiol. 2010. PMID: 20143946 Free PMC article. Review.
SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.
Petrovas C, Price DA, Mattapallil J, Ambrozak DR, Geldmacher C, Cecchinato V, Vaccari M, Tryniszewska E, Gostick E, Roederer M, Douek DC, Morgan SH, Davis SJ, Franchini G, Koup RA. Petrovas C, et al. Among authors: franchini g. Blood. 2007 Aug 1;110(3):928-36. doi: 10.1182/blood-2007-01-069112. Epub 2007 Apr 17. Blood. 2007. PMID: 17440051 Free PMC article.
CD4+ T-cell loss and delayed expression of modulators of immune responses at mucosal sites of vaccinated macaques following SIV(mac251) infection.
Vaccari M, Boasso A, Ma ZM, Cecchinato V, Venzon D, Doster MN, Tsai WP, Shearer GM, Fuchs D, Felber BK, Pavlakis GN, Miller CJ, Franchini G. Vaccari M, et al. Among authors: franchini g. Mucosal Immunol. 2008 Nov;1(6):497-507. doi: 10.1038/mi.2008.60. Epub 2008 Sep 17. Mucosal Immunol. 2008. PMID: 19079217 Free PMC article.
Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia.
Gordon SN, Doster MN, Kines RC, Keele BF, Brocca-Cofano E, Guan Y, Pegu P, Liyanage NP, Vaccari M, Cuburu N, Buck CB, Ferrari G, Montefiori D, Piatak M Jr, Lifson JD, Xenophontos AM, Venzon D, Robert-Guroff M, Graham BS, Lowy DR, Schiller JT, Franchini G. Gordon SN, et al. Among authors: franchini g. J Immunol. 2014 Dec 15;193(12):6172-83. doi: 10.4049/jimmunol.1401504. Epub 2014 Nov 14. J Immunol. 2014. PMID: 25398324 Free PMC article.
Potentiation of simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen.
Hel Z, Tsai WP, Thornton A, Nacsa J, Giuliani L, Tryniszewska E, Poudyal M, Venzon D, Wang X, Altman J, Watkins DI, Lu W, von Gegerfelt A, Felber BK, Tartaglia J, Pavlakis GN, Franchini G. Hel Z, et al. Among authors: franchini g. J Immunol. 2001 Dec 15;167(12):7180-91. doi: 10.4049/jimmunol.167.12.7180. J Immunol. 2001. PMID: 11739541
Modeling a safer smallpox vaccination regimen, for human immunodeficiency virus type 1-infected patients, in immunocompromised macaques.
Edghill-Smith Y, Venzon D, Karpova T, McNally J, Nacsa J, Tsai WP, Tryniszewska E, Moniuszko M, Manischewitz J, King LR, Snodgrass SJ, Parrish J, Markham P, Sowers M, Martin D, Lewis MG, Berzofsky JA, Belyakov IM, Moss B, Tartaglia J, Bray M, Hirsch V, Golding H, Franchini G. Edghill-Smith Y, et al. Among authors: franchini g. J Infect Dis. 2003 Oct 15;188(8):1181-91. doi: 10.1086/378518. Epub 2003 Oct 10. J Infect Dis. 2003. PMID: 14551889
390 results