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Quercetin prevents liver carcinogenesis by inducing cell cycle arrest, decreasing cell proliferation and enhancing apoptosis.
Casella ML, Parody JP, Ceballos MP, Quiroga AD, Ronco MT, Francés DE, Monti JA, Pisani GB, Carnovale CE, Carrillo MC, de Luján Alvarez M. Casella ML, et al. Among authors: frances de, de lujan alvarez m. Mol Nutr Food Res. 2014 Feb;58(2):289-300. doi: 10.1002/mnfr.201300362. Epub 2013 Oct 1. Mol Nutr Food Res. 2014. PMID: 24124108
Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet.
Lambertucci F, Arboatti A, Sedlmeier MG, Motiño O, Alvarez ML, Ceballos MP, Villar SR, Roggero E, Monti JA, Pisani G, Quiroga AD, Martín-Sanz P, Carnovale CE, Francés DE, Ronco MT. Lambertucci F, et al. Among authors: frances de. J Nutr Biochem. 2018 Aug;58:17-27. doi: 10.1016/j.jnutbio.2018.04.013. Epub 2018 May 2. J Nutr Biochem. 2018. PMID: 29860102 Free article.
Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis.
Lambertucci F, Motiño O, Villar S, Rigalli JP, de Luján Alvarez M, Catania VA, Martín-Sanz P, Carnovale CE, Quiroga AD, Francés DE, Ronco MT. Lambertucci F, et al. Among authors: frances de. Toxicol Appl Pharmacol. 2017 Jan 15;315:12-22. doi: 10.1016/j.taap.2016.11.015. Epub 2016 Nov 27. Toxicol Appl Pharmacol. 2017. PMID: 27899278
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p.
Brea R, Motiño O, Francés D, García-Monzón C, Vargas J, Fernández-Velasco M, Boscá L, Casado M, Martín-Sanz P, Agra N. Brea R, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):325-337. doi: 10.1016/j.bbadis.2017.11.001. Epub 2017 Nov 3. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29109031 Free article.
NOD1 receptor is up-regulated in diabetic human and murine myocardium.
Prieto P, Vallejo-Cremades MT, Benito G, González-Peramato P, Francés D, Agra N, Terrón V, Gónzalez-Ramos S, Delgado C, Ruiz-Gayo M, Pacheco I, Velasco-Martín JP, Regadera J, Martín-Sanz P, López-Collazo E, Boscá L, Fernández-Velasco M. Prieto P, et al. Clin Sci (Lond). 2014 Dec;127(12):665-77. doi: 10.1042/CS20140180. Clin Sci (Lond). 2014. PMID: 24934088
Editorial: New Insights Into Understanding and Managing NAFLD.
Escribano Ó, Francés DE, Otero YF, Egea J, González-Rodríguez Á. Escribano Ó, et al. Among authors: frances de. Front Med (Lausanne). 2021 Nov 12;8:777740. doi: 10.3389/fmed.2021.777740. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34869497 Free PMC article. No abstract available.
28 results