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653 results

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Page 1
Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling.
Deroche L, Aranzana-Climent V, Rozenholc A, Prouvensier L, Darnaud L, Grégoire N, Marchand S, Ploy M-C, François B, Couet W, Barraud O, Buyck JM. Deroche L, et al. Among authors: francois b. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0048023. doi: 10.1128/aac.00480-23. Epub 2023 Sep 11. Antimicrob Agents Chemother. 2023. PMID: 37695298 Free PMC article.
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial.
Chastre J, François B, Bourgeois M, Komnos A, Ferrer R, Rahav G, De Schryver N, Lepape A, Koksal I, Luyt CE, Sánchez-García M, Torres A, Eggimann P, Koulenti D, Holland TL, Ali O, Shoemaker K, Ren P, Sauser J, Ruzin A, Tabor DE, Akhgar A, Wu Y, Jiang Y, DiGiandomenico A, Colbert S, Vandamme D, Coenjaerts F, Malhotra-Kumar S, Timbermont L, Oliver A, Barraud O, Bellamy T, Bonten M, Goossens H, Reisner C, Esser MT, Jafri HS; COMBACTE-MAGNET EVADE Study Group. Chastre J, et al. Among authors: francois b. Crit Care. 2022 Nov 15;26(1):355. doi: 10.1186/s13054-022-04204-9. Crit Care. 2022. PMID: 36380312 Free PMC article. Clinical Trial.
Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients.
Gibot S, Lafon T, Jacquin L, Lefevre B, Kimmoun A, Guillaumot A, Losser MR, Douplat M, Argaud L, De Ciancio G, Jolly L, Touly N, Derive M, Malaplate C, Luc A, Baumann C, François B. Gibot S, et al. Among authors: francois b. Intensive Care Med Exp. 2023 Aug 14;11(1):51. doi: 10.1186/s40635-023-00532-4. Intensive Care Med Exp. 2023. PMID: 37574520 Free PMC article.
De novo natural anti-M alloantibody emergence in severe Coronavirus Disease 2019.
Jeannet R, Descazeaud A, Daix T, Pauthier H, Pascal V, Hantz S, Cam SL, Francois B, Feuillard J, Lafarge X. Jeannet R, et al. Among authors: francois b. J Infect Public Health. 2022 Dec;15(12):1455-1458. doi: 10.1016/j.jiph.2022.10.025. Epub 2022 Nov 2. J Infect Public Health. 2022. PMID: 36403401 Free PMC article.
Hydrocortisone in Severe Community-Acquired Pneumonia.
Dequin PF, Meziani F, Quenot JP, Kamel T, Ricard JD, Badie J, Reignier J, Heming N, Plantefève G, Souweine B, Voiriot G, Colin G, Frat JP, Mira JP, Barbarot N, François B, Louis G, Gibot S, Guitton C, Giacardi C, Hraiech S, Vimeux S, L'Her E, Faure H, Herbrecht JE, Bouisse C, Joret A, Terzi N, Gacouin A, Quentin C, Jourdain M, Leclerc M, Coffre C, Bourgoin H, Lengellé C, Caille-Fénérol C, Giraudeau B, Le Gouge A; CRICS-TriGGERSep Network. Dequin PF, et al. Among authors: francois b. N Engl J Med. 2023 May 25;388(21):1931-1941. doi: 10.1056/NEJMoa2215145. Epub 2023 Mar 21. N Engl J Med. 2023. PMID: 36942789 Clinical Trial.
Long-term immunosuppressive treatment is not associated with worse outcome in patients hospitalized in the intensive care unit for septic shock: the PACIFIC study.
Vaidie J, Peju E, Jandeaux LM, Lesouhaitier M, Lacherade JC, Guillon A, Wittebole X, Asfar P, Evrard B, Daix T, Vignon P, François B. Vaidie J, et al. Among authors: francois b. Crit Care. 2023 Sep 2;27(1):340. doi: 10.1186/s13054-023-04626-z. Crit Care. 2023. PMID: 37660107 Free PMC article.
Echocardiography phenotypes of right ventricular involvement in COVID-19 ARDS patients and ICU mortality: post-hoc (exploratory) analysis of repeated data from the ECHO-COVID study.
Huang S, Vieillard-Baron A, Evrard B, Prat G, Chew MS, Balik M, Clau-Terré F, De Backer D, Mekontso Dessap A, Orde S, Morelli A, Sanfilippo F, Charron C, Vignon P; ECHO-COVID study group. Huang S, et al. Intensive Care Med. 2023 Aug;49(8):946-956. doi: 10.1007/s00134-023-07147-z. Epub 2023 Jul 12. Intensive Care Med. 2023. PMID: 37436445
Interferon gamma-1b for the prevention of hospital-acquired pneumonia in critically ill patients: a phase 2, placebo-controlled randomized clinical trial.
Roquilly A, Francois B, Huet O, Launey Y, Lasocki S, Weiss E, Petrier M, Hourmant Y, Bouras M, Lakhal K, Le Bel C, Flattres Duchaussoy D, Fernández-Barat L, Ceccato A, Flet L, Jobert A, Poschmann J, Sebille V, Feuillet F, Koulenti D, Torres A; Atlanrea study group and the Société Française d’Anesthésie Réanimation (SFAR) Research Network. Roquilly A, et al. Among authors: francois b. Intensive Care Med. 2023 May;49(5):530-544. doi: 10.1007/s00134-023-07065-0. Epub 2023 Apr 18. Intensive Care Med. 2023. PMID: 37072597 Free PMC article. Clinical Trial.
Restrictive use of Restraints and Delirium Duration in the Intensive Care Unit (R2D2-ICU): protocol for a French multicentre parallel-group open-label randomised controlled trial.
Sonneville R, Couffignal C, Sigaud F, Godard V, Audibert J, Contou D, Celier A, Djibre M, Schmidt J, Jaquet P, Mekontso Dessap A, Bourel C, Bellot R, Roy C, Lamara F, Essardy F, Timsit JF, Cornic R, Bouadma L; R2D2-ICU investigators. Sonneville R, et al. BMJ Open. 2024 Apr 17;14(4):e083414. doi: 10.1136/bmjopen-2023-083414. BMJ Open. 2024. PMID: 38631841 Free PMC article.
653 results