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Page 1
Matrix Metalloproteinases on Severe COVID-19 Lung Disease Pathogenesis: Cooperative Actions of MMP-8/MMP-2 Axis on Immune Response through HLA-G Shedding and Oxidative Stress.
da Silva-Neto PV, do Valle VB, Fuzo CA, Fernandes TM, Toro DM, Fraga-Silva TFC, Basile PA, de Carvalho JCS, Pimentel VE, Pérez MM, Oliveira CNS, Rodrigues LC, Bastos VAF, Tella SOC, Martins RB, Degiovani AM, Ostini FM, Feitosa MR, Parra RS, Vilar FC, Gaspar GG, Rocha JJRD, Feres O, Arruda E, Maruyama SR, Russo EMS, Viana AL, Santos IKFM, Bonato VLD, Cardoso CRB, Tanus-Santos JE, Donadi EA, Faccioli LH, Dias-Baruffi M, Fernandes APM, Gerlach RF, Sorgi CA, On Behalf Of The Immunocovid Study Group. da Silva-Neto PV, et al. Biomolecules. 2022 Apr 19;12(5):604. doi: 10.3390/biom12050604. Biomolecules. 2022. PMID: 35625532 Free PMC article.
Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients.
Potje SR, Costa TJ, Fraga-Silva TFC, Martins RB, Benatti MN, Almado CEL, de Sá KSG, Bonato VLD, Arruda E, Louzada-Junior P, Oliveira RDR, Zamboni DS, Becari C, Auxiliadora-Martins M, Tostes RC. Potje SR, et al. Life Sci. 2021 Jul 1;276:119376. doi: 10.1016/j.lfs.2021.119376. Epub 2021 Mar 27. Life Sci. 2021. PMID: 33781826 Free PMC article.
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.
Costa TJ, Potje SR, Fraga-Silva TFC, da Silva-Neto JA, Barros PR, Rodrigues D, Machado MR, Martins RB, Santos-Eichler RA, Benatti MN, de Sá KSG, Almado CEL, Castro ÍA, Pontelli MC, Serra L, Carneiro FS, Becari C, Louzada-Junior P, Oliveira RDR, Zamboni DS, Arruda E, Auxiliadora-Martins M, Giachini FRC, Bonato VLD, Zachara NE, Bomfim GF, Tostes RC. Costa TJ, et al. Vascul Pharmacol. 2022 Feb;142:106946. doi: 10.1016/j.vph.2021.106946. Epub 2021 Nov 25. Vascul Pharmacol. 2022. PMID: 34838735 Free PMC article.
sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity.
da Silva-Neto PV, de Carvalho JCS, Pimentel VE, Pérez MM, Toro DM, Fraga-Silva TFC, Fuzo CA, Oliveira CNS, Rodrigues LC, Argolo JGM, Carmona-Garcia I, Neto NT, Souza COS, Fernandes TM, Bastos VAF, Degiovani AM, Constant LF, Ostini FM, Feitosa MR, Parra RS, Vilar FC, Gaspar GG, da Rocha JJR, Feres O, Frantz FG, Gerlach RF, Maruyama SR, Russo EMS, Viana AL, Fernandes APM, Santos IKFM, Bonato VLD, Boechat AL, Malheiro A, Sadikot RT, Dias-Baruffi M, Cardoso CRB, Faccioli LH, Sorgi CA, On Behalf Of The Imunocovid Study Group. da Silva-Neto PV, et al. Viruses. 2021 Dec 15;13(12):2521. doi: 10.3390/v13122521. Viruses. 2021. PMID: 34960790 Free PMC article.
Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity.
Pérez MM, Pimentel VE, Fuzo CA, da Silva-Neto PV, Toro DM, Fraga-Silva TFC, Gardinassi LG, Oliveira CNS, Souza COS, Torre-Neto NT, de Carvalho JCS, De Leo TC, Nardini V, Feitosa MR, Parra RS, da Rocha JJR, Feres O, Vilar FC, Gaspar GG, Constant LF, Ostini FM, Degiovani AM, Amorim AP, Viana AL, Fernandes APM, Maruyama SR, Russo EMS, Santos IKFM, Bonato VLD, Cardoso CRB, Sorgi CA, Dias-Baruffi M, Faccioli LH; ImmunoCOVID Brazilian Research Consortium. Pérez MM, et al. J Immunol. 2022 Jul 15;209(2):250-261. doi: 10.4049/jimmunol.2200079. Epub 2022 Jun 29. J Immunol. 2022. PMID: 35768148
Celastrol: A lead compound that inhibits SARS-CoV-2 replication, the activity of viral and human cysteine proteases, and virus-induced IL-6 secretion.
Fuzo CA, Martins RB, Fraga-Silva TFC, Amstalden MK, Canassa De Leo T, Souza JP, Lima TM, Faccioli LH, Okamoto DN, Juliano MA, França SC, Juliano L, Bonato VLD, Arruda E, Dias-Baruffi M. Fuzo CA, et al. Drug Dev Res. 2022 Nov;83(7):1623-1640. doi: 10.1002/ddr.21982. Epub 2022 Aug 21. Drug Dev Res. 2022. PMID: 35989498 Free PMC article.
The Severity of COVID-19 Affects the Plasma Soluble Levels of the Immune Checkpoint HLA-G Molecule.
Cordeiro JFC, Fernandes TM, Toro DM, da Silva-Neto PV, Pimentel VE, Pérez MM, de Carvalho JCS, Fraga-Silva TFC, Oliveira CNS, Argolo JGM, Degiovani AM, Ostini FM, Puginna EF, da Silva JS, Santos IKFM, Bonato VLD, Cardoso CRB, Dias-Baruffi M, Faccioli LH, Donadi EA, Sorgi CA, Fernandes APM, On Behalf Of The Immunocovid Study Group. Cordeiro JFC, et al. Int J Mol Sci. 2022 Aug 27;23(17):9736. doi: 10.3390/ijms23179736. Int J Mol Sci. 2022. PMID: 36077133 Free PMC article.
The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity.
Siekman SL, Pongracz T, Wang W, Nouta J, Kremsner PG, da Silva-Neto PV, Esen M, Kreidenweiss A, Held J, Trapé ÁA, Fendel R, de Miranda Santos IKF, Wuhrer M; ImmunoCovid Consortium. Siekman SL, et al. Front Immunol. 2022 Oct 18;13:993354. doi: 10.3389/fimmu.2022.993354. eCollection 2022. Front Immunol. 2022. PMID: 36389824 Free PMC article.
Cell death induced by NLRP3-palmitate axis impairs pulmonary damage tolerance and aggravates immunopathology during obesity-tuberculosis comorbidity.
Palma Albornoz SP, Fraga-Silva TF, de Carvalho RV, Rodrigues TS, Gembre AF, de Oliveira RS, de Souza FM, Corrêa GF, Ramalho LN, Carlos D, de Almeida DC, Câmara NO, Zamboni DS, Takahashi VN, Sorgi CA, Faccioli LH, Medeiros AI, Costa DL, Bonato VL. Palma Albornoz SP, et al. J Pathol. 2023 Mar;259(3):291-303. doi: 10.1002/path.6041. Epub 2023 Jan 3. J Pathol. 2023. PMID: 36441400
46 results