Fraga CA - Search Results

1

Filtering promiscuous compounds in early drug discovery: is it a good idea?

Senger MR, Fraga CA, Dantas RF, Silva FP Jr. Senger MR, et al. Among authors: fraga ca. Drug Discov Today. 2016 Jun;21(6):868-72. doi: 10.1016/j.drudis.2016.02.004. Epub 2016 Feb 12. Drug Discov Today. 2016. PMID: 26880580

2

Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2-a]pyridine symbiotic prototypes.

Lacerda RB, de Lima CK, da Silva LL, Romeiro NC, Miranda AL, Barreiro EJ, Fraga CA. Lacerda RB, et al. Among authors: fraga ca. Bioorg Med Chem. 2009 Jan 1;17(1):74-84. doi: 10.1016/j.bmc.2008.11.018. Epub 2008 Nov 17. Bioorg Med Chem. 2009. PMID: 19059783

3

Privileged structures: a useful concept for the rational design of new lead drug candidates.

Duarte CD, Barreiro EJ, Fraga CA. Duarte CD, et al. Among authors: fraga ca. Mini Rev Med Chem. 2007 Nov;7(11):1108-19. doi: 10.2174/138955707782331722. Mini Rev Med Chem. 2007. PMID: 18045214 Review.

4

Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin.

Avila CM, Romeiro NC, Sant'Anna CM, Barreiro EJ, Fraga CA. Avila CM, et al. Among authors: fraga ca. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6907-10. doi: 10.1016/j.bmcl.2009.10.076. Epub 2009 Oct 22. Bioorg Med Chem Lett. 2009. PMID: 19896375

5

Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype.

Rodrigues AP, Costa LM, Santos BL, Maia RC, Miranda AL, Barreiro EJ, Fraga CA. Rodrigues AP, et al. Among authors: fraga ca. J Enzyme Inhib Med Chem. 2012 Feb;27(1):101-9. doi: 10.3109/14756366.2011.578575. Epub 2011 May 25. J Enzyme Inhib Med Chem. 2012. PMID: 21612374

6

Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

Freitas RHCN, Cordeiro NM, Carvalho PR, Alves MA, Guedes IA, Valerio TS, Dardenne LE, Lima LM, Barreiro EJ, Fernandes PD, Fraga CAM. Freitas RHCN, et al. Chem Biol Drug Des. 2018 Feb;91(2):391-397. doi: 10.1111/cbdd.13085. Epub 2017 Sep 10. Chem Biol Drug Des. 2018. PMID: 28815968

7

NF-κB-IKKβ Pathway as a Target for Drug Development: Realities, Challenges and Perspectives.

Freitas RHCN, Fraga CAM. Freitas RHCN, et al. Curr Drug Targets. 2018;19(16):1933-1942. doi: 10.2174/1389450119666180219120534. Curr Drug Targets. 2018. PMID: 29468963 Review.

8

N-Acylhydrazones as drugs.

Thota S, Rodrigues DA, Pinheiro PSM, Lima LM, Fraga CAM, Barreiro EJ. Thota S, et al. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2797-2806. doi: 10.1016/j.bmcl.2018.07.015. Epub 2018 Jul 9. Bioorg Med Chem Lett. 2018. PMID: 30006065 Review.

9

The Use of Conformational Restriction in Medicinal Chemistry.

de Sena M Pinheiro P, Rodrigues DA, do Couto Maia R, Thota S, Fraga CAM. de Sena M Pinheiro P, et al. Curr Top Med Chem. 2019;19(19):1712-1733. doi: 10.2174/1568026619666190712205025. Curr Top Med Chem. 2019. PMID: 31659944 Review.

10

Partial agonism and fast dissociation of LASSBio-579 at dopamine D2 receptor.

Pompeu TE, Monteiro do Monte F, Bosier B, Fraga CA, Barreiro EJ, Menegatti R, Hermans E, Noël F. Pompeu TE, et al. Among authors: fraga ca. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:1-6. doi: 10.1016/j.pnpbp.2015.04.003. Epub 2015 Apr 17. Prog Neuropsychopharmacol Biol Psychiatry. 2015. PMID: 25891249 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

193 results

Search Page