Fracasso RP - Search Results

1

Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946).

Scott WJ, Hentemann MF, Rowley RB, Bull CO, Jenkins S, Bullion AM, Johnson J, Redman A, Robbins AH, Esler W, Fracasso RP, Garrison T, Hamilton M, Michels M, Wood JE, Wilkie DP, Xiao H, Levy J, Stasik E, Liu N, Schaefer M, Brands M, Lefranc J. Scott WJ, et al. Among authors: fracasso rp. ChemMedChem. 2016 Jul 19;11(14):1517-30. doi: 10.1002/cmdc.201600148. Epub 2016 Jun 16. ChemMedChem. 2016. PMID: 27310202 Free PMC article.

2

Klotho May Ameliorate Proteinuria by Targeting TRPC6 Channels in Podocytes.

Kim JH, Xie J, Hwang KH, Wu YL, Oliver N, Eom M, Park KS, Barrezueta N, Kong ID, Fracasso RP, Huang CL, Cha SK. Kim JH, et al. Among authors: fracasso rp. J Am Soc Nephrol. 2017 Jan;28(1):140-151. doi: 10.1681/ASN.2015080888. Epub 2016 May 5. J Am Soc Nephrol. 2017. PMID: 27151926 Free PMC article.

3

Inhibition of PHF-like tau hyperphosphorylation in SH-SY5Y cells and rat brain slices by K252a.

Hübinger G, Geis S, LeCorre S, Mühlbacher S, Gordon S, Fracasso RP, Hoffman F, Ferrand S, Klafki HW, Roder HM. Hübinger G, et al. Among authors: fracasso rp. J Alzheimers Dis. 2008 Apr;13(3):281-94. doi: 10.3233/jad-2008-13306. J Alzheimers Dis. 2008. PMID: 18430996

4

Phosphorylation-dependent monoclonal Tau antibodies do not reliably report phosphorylation by extracellular signal-regulated kinase 2 at specific sites.

Roder HM, Fracasso RP, Hoffman FJ, Witowsky JA, Davis G, Pellegrino CB. Roder HM, et al. Among authors: fracasso rp. J Biol Chem. 1997 Feb 14;272(7):4509-15. doi: 10.1074/jbc.272.7.4509. J Biol Chem. 1997. PMID: 9020176 Free article.

5

Age-associated inclusions in normal and transgenic mouse brain.

Wirak D, Bayney R, Ramabhadran TV, Fracasso RP, Hart JT, Hauer PE, Hsiau P, Pekar SK, Scangos GA, Trapp BD, Unterbeck AJ. Wirak D, et al. Among authors: fracasso rp. Science. 1992 Mar 13;255(5050):1445. doi: 10.1126/science.255.5050.1445. Science. 1992. PMID: 17801233 No abstract available.

6

Use of recombinant fusion proteins for generation and rapid characterization of monoclonal antibodies. Application to the Kunitz domain of human beta amyloid precursor protein.

Wunderlich D, Lee A, Fracasso RP, Mierz DV, Bayney RM, Ramabhadran TV. Wunderlich D, et al. Among authors: fracasso rp. J Immunol Methods. 1992 Feb 14;147(1):1-11. doi: 10.1016/s0022-1759(12)80022-6. J Immunol Methods. 1992. PMID: 1371794

7

Deposits of amyloid beta protein in the central nervous system of transgenic mice.

Wirak DO, Bayney R, Ramabhadran TV, Fracasso RP, Hart JT, Hauer PE, Hsiau P, Pekar SK, Scangos GA, Trapp BD, et al. Wirak DO, et al. Among authors: fracasso rp. Science. 1991 Jul 19;253(5017):323-5. doi: 10.1126/science.1857970. Science. 1991. PMID: 1857970

8

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.

Buxbaum JD, Gandy SE, Cicchetti P, Ehrlich ME, Czernik AJ, Fracasso RP, Ramabhadran TV, Unterbeck AJ, Greengard P. Buxbaum JD, et al. Among authors: fracasso rp. Proc Natl Acad Sci U S A. 1990 Aug;87(15):6003-6. doi: 10.1073/pnas.87.15.6003. Proc Natl Acad Sci U S A. 1990. PMID: 2116015 Free PMC article.

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