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Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.
Nat Immunol. 2023 Jul;24(7):1124-1137. doi: 10.1038/s41590-023-01519-9. Epub 2023 May 22.
Nat Immunol. 2023.
PMID: 37217705
Free PMC article.
B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction.
Lee JL, Fra-Bido SC, Burton AR, Innocentin S, Hill DL, Linterman MA.
Lee JL, et al. Among authors: fra bido sc.
Aging Cell. 2022 Sep;21(9):e13692. doi: 10.1111/acel.13692. Epub 2022 Aug 18.
Aging Cell. 2022.
PMID: 35980826
Free PMC article.
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Targeting TLR4 during vaccination boosts MAdCAM-1+ lymphoid stromal cell activation and promotes the aged germinal center response.
Denton AE, Dooley J, Cinti I, Silva-Cayetano A, Fra-Bido S, Innocentin S, Hill DL, Carr EJ, McKenzie ANJ, Liston A, Linterman MA.
Denton AE, et al. Among authors: fra bido s.
Sci Immunol. 2022 May 6;7(71):eabk0018. doi: 10.1126/sciimmunol.abk0018. Epub 2022 May 6.
Sci Immunol. 2022.
PMID: 35522725
Free PMC article.
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Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice.
Fra-Bido S, Walker SA, Innocentin S, Linterman MA.
Fra-Bido S, et al.
STAR Protoc. 2021 Jun 18;2(3):100499. doi: 10.1016/j.xpro.2021.100499. eCollection 2021 Sep 17.
STAR Protoc. 2021.
PMID: 34195671
Free PMC article.
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A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.
Silva-Cayetano A, Foster WS, Innocentin S, Belij-Rammerstorfer S, Spencer AJ, Burton OT, Fra-Bidó S, Le Lee J, Thakur N, Conceicao C, Wright D, Barrett J, Evans-Bailey N, Noble C, Bailey D, Liston A, Gilbert SC, Lambe T, Linterman MA.
Silva-Cayetano A, et al. Among authors: fra bido s.
Med. 2021 Mar 12;2(3):243-262.e8. doi: 10.1016/j.medj.2020.12.006. Epub 2020 Dec 16.
Med. 2021.
PMID: 33521747
Free PMC article.
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Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ.
Webb LMC, Fra-Bido S, Innocentin S, Matheson LS, Attaf N, Bignon A, Novarino J, Fazilleau N, Linterman MA.
Webb LMC, et al. Among authors: fra bido s.
Aging Cell. 2021 Jan;20(1):e13295. doi: 10.1111/acel.13295. Epub 2021 Jan 2.
Aging Cell. 2021.
PMID: 33387451
Free PMC article.
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Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.
Vanderleyden I, Fra-Bido SC, Innocentin S, Stebegg M, Okkenhaug H, Evans-Bailey N, Pierson W, Denton AE, Linterman MA.
Vanderleyden I, et al. Among authors: fra bido sc.
Cell Rep. 2020 Jan 21;30(3):611-619.e4. doi: 10.1016/j.celrep.2019.12.076.
Cell Rep. 2020.
PMID: 31968240
Free PMC article.
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