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Formulation, inflammation, and RNA sensing impact the immunogenicity of self-amplifying RNA vaccines.
Tregoning JS, Stirling DC, Wang Z, Flight KE, Brown JC, Blakney AK, McKay PF, Cunliffe RF, Murugaiah V, Fox CB, Beattie M, Tam YK, Johansson C, Shattock RJ. Tregoning JS, et al. Among authors: fox cb. Mol Ther Nucleic Acids. 2022 Dec 5;31:29-42. doi: 10.1016/j.omtn.2022.11.024. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2022. PMID: 36589712 Free PMC article.
A structure-function approach to optimizing TLR4 ligands for human vaccines.
Carter D, Fox CB, Day TA, Guderian JA, Liang H, Rolf T, Vergara J, Sagawa ZK, Ireton G, Orr MT, Desbien A, Duthie MS, Coler RN, Reed SG. Carter D, et al. Among authors: fox cb. Clin Transl Immunology. 2016 Nov 2;5(11):e108. doi: 10.1038/cti.2016.63. eCollection 2016 Nov. Clin Transl Immunology. 2016. PMID: 27990284 Free PMC article.
A Nanostructured Lipid Carrier for Delivery of a Replicating Viral RNA Provides Single, Low-Dose Protection against Zika.
Erasmus JH, Khandhar AP, Guderian J, Granger B, Archer J, Archer M, Gage E, Fuerte-Stone J, Larson E, Lin S, Kramer R, Coler RN, Fox CB, Stinchcomb DT, Reed SG, Van Hoeven N. Erasmus JH, et al. Among authors: fox cb. Mol Ther. 2018 Oct 3;26(10):2507-2522. doi: 10.1016/j.ymthe.2018.07.010. Epub 2018 Aug 2. Mol Ther. 2018. PMID: 30078765 Free PMC article.
Use of defined TLR ligands as adjuvants within human vaccines.
Duthie MS, Windish HP, Fox CB, Reed SG. Duthie MS, et al. Among authors: fox cb. Immunol Rev. 2011 Jan;239(1):178-96. doi: 10.1111/j.1600-065X.2010.00978.x. Immunol Rev. 2011. PMID: 21198672 Free PMC article. Review.
152 results