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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Gallo D, Young JTF, Fourtounis J, Martino G, Álvarez-Quilón A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugère-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkáč J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D. Gallo D, et al. Among authors: fournier s. Nature. 2022 Apr;604(7907):749-756. doi: 10.1038/s41586-022-04638-9. Epub 2022 Apr 20. Nature. 2022. PMID: 35444283 Free PMC article.
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
Roulston A, Zimmermann M, Papp R, Skeldon A, Pellerin C, Dumas-Bérube É, Dumais V, Dorich S, Fader LD, Fournier S, Li L, Leclaire ME, Yin SY, Chefson A, Alam H, Yang W, Fugère-Desjardins C, Vignini-Hammond S, Skorey K, Mulani A, Rimkunas V, Veloso A, Hamel M, Stocco R, Mamane Y, Li Z, Young JTF, Zinda M, Black WC. Roulston A, et al. Among authors: fournier s. Mol Cancer Ther. 2022 Feb;21(2):245-256. doi: 10.1158/1535-7163.MCT-21-0615. Epub 2021 Dec 15. Mol Cancer Ther. 2022. PMID: 34911817 Free PMC article.
Guiding ATR and PARP inhibitor combinationswith chemogenomic screens.
Zimmermann M, Bernier C, Kaiser B, Fournier S, Li L, Desjardins J, Skeldon A, Rimkunas V, Veloso A, Young JTF, Roulston A, Zinda M. Zimmermann M, et al. Among authors: fournier s. Cell Rep. 2022 Jul 12;40(2):111081. doi: 10.1016/j.celrep.2022.111081. Cell Rep. 2022. PMID: 35830811 Free article.
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500).
Black WC, Abdoli A, An X, Auger A, Beaulieu P, Bernatchez M, Caron C, Chefson A, Crane S, Diallo M, Dorich S, Fader LD, Ferraro GB, Fournier S, Gao Q, Ginzburg Y, Hamel M, Han Y, Jones P, Lanoix S, Lacbay CM, Leclaire ME, Levy M, Mamane Y, Mulani A, Papp R, Pellerin C, Picard A, Skeldon A, Skorey K, Stocco R, St-Onge M, Truchon JF, Truong VL, Zimmermann M, Zinda M, Roulston A. Black WC, et al. Among authors: fournier s. J Med Chem. 2024 Feb 22;67(4):2349-2368. doi: 10.1021/acs.jmedchem.3c01917. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38299539
The Pediatric Autism Research Cohort (PARC) Study: protocol for a patient-oriented prospective study examining trajectories of functioning in children with autism.
Kata A, McPhee PG, Chen YJ, Zwaigenbaum L, Singal D, Roncadin C, Bennett T, Carter M, Di Rezze B, Drmic I, Duku E, Fournier S, Frei J, Gentles SJ, Georgiades K, Hanlon-Dearman A, Hoult L, Kelley E, Koller J, de Camargo OK, Lai J, Mahoney B, Mesterman R, Ng O, Robertson S, Rosenbaum P, Salt M, Zubairi MS, Georgiades S. Kata A, et al. Among authors: fournier s. BMJ Open. 2024 Apr 29;14(4):e083045. doi: 10.1136/bmjopen-2023-083045. BMJ Open. 2024. PMID: 38684247 Free PMC article.
A study of ChatGPT in facilitating Heart Team decisions on severe aortic stenosis.
Salihu A, Meier D, Noirclerc N, Skalidis I, Mauler-Wittwer S, Recordon F, Kirsch M, Roguelov C, Berger A, Sun X, Abbe E, Marcucci C, Rancati V, Rosner L, Scala E, Rotzinger DC, Humbert M, Muller O, Lu H, Fournier S. Salihu A, et al. Among authors: fournier s. EuroIntervention. 2024 Apr 15;20(8):e496-e503. doi: 10.4244/EIJ-D-23-00643. EuroIntervention. 2024. PMID: 38629422 Free article.
History of smallpox vaccination and marked clinical expression of mpox among cases notified in France from May to July 2022.
Krug C, Chazelle E, Tarantola A, Noël H, Spaccaferri G, Parent du Châtelet I, Zanetti L, Lahbib H, Fayad M, Lot F, De Valk H, Che D, Coignard B, Mailles A, Barret AS; Investigation Team. Krug C, et al. Clin Microbiol Infect. 2024 Apr 7:S1198-743X(24)00169-1. doi: 10.1016/j.cmi.2024.03.038. Online ahead of print. Clin Microbiol Infect. 2024. PMID: 38588877
444 results