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161 results

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Page 1
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life.
Hata M, Hata M, Andriessen EM, Juneau R, Pilon F, Crespo-Garcia S, Diaz-Marin R, Guber V, Binet F, Fournier F, Buscarlet M, Grou C, Calderon V, Heckel E, Melichar HJ, Joyal JS, Wilson AM, Sapieha P. Hata M, et al. Among authors: fournier f. J Clin Invest. 2023 Feb 15;133(4):e159757. doi: 10.1172/JCI159757. J Clin Invest. 2023. PMID: 36787231 Free PMC article.
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.
Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, Chaney SY, Pilon F, Dogan T, Cagnone G, Patel P, Buscarlet M, Dasgupta S, Girouard G, Rao SR, Wilson AM, O'Brien R, Juneau R, Guber V, Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P. Crespo-Garcia S, et al. Among authors: fournier f. Cell Metab. 2021 Apr 6;33(4):818-832.e7. doi: 10.1016/j.cmet.2021.01.011. Epub 2021 Feb 5. Cell Metab. 2021. PMID: 33548171 Free article.
Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation.
Andriessen EMMA, Binet F, Fournier F, Hata M, Dejda A, Mawambo G, Crespo-Garcia S, Pilon F, Buscarlet M, Beauchemin K, Bougie V, Cumberlidge G, Wilson AM, Bourgault S, Rezende FA, Beaulieu N, Delisle JS, Sapieha P. Andriessen EMMA, et al. Among authors: fournier f. EMBO Mol Med. 2021 May 7;13(5):e11754. doi: 10.15252/emmm.201911754. Epub 2021 Apr 19. EMBO Mol Med. 2021. PMID: 33876574 Free PMC article.
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.
Diaz-Marin R, Crespo-Garcia S, Wilson AM, Buscarlet M, Dejda A, Fournier F, Juneau R, Alquier T, Sapieha P. Diaz-Marin R, et al. Among authors: fournier f. Sci Rep. 2021 Aug 3;11(1):15767. doi: 10.1038/s41598-021-95064-w. Sci Rep. 2021. PMID: 34344941 Free PMC article.
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation.
Hata M, Andriessen EMMA, Hata M, Diaz-Marin R, Fournier F, Crespo-Garcia S, Blot G, Juneau R, Pilon F, Dejda A, Guber V, Heckel E, Daneault C, Calderon V, Des Rosiers C, Melichar HJ, Langmann T, Joyal JS, Wilson AM, Sapieha P. Hata M, et al. Among authors: fournier f. Science. 2023 Jan 6;379(6627):45-62. doi: 10.1126/science.abj8894. Epub 2023 Jan 5. Science. 2023. PMID: 36603072
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results.
Crespo-Garcia S, Fournier F, Diaz-Marin R, Klier S, Ragusa D, Masaki L, Cagnone G, Blot G, Hafiane I, Dejda A, Rizk R, Juneau R, Buscarlet M, Chorfi S, Patel P, Beltran PJ, Joyal JS, Rezende FA, Hata M, Nguyen A, Sullivan L, Damiano J, Wilson AM, Mallette FA, David NE, Ghosh A, Tsuruda PR, Dananberg J, Sapieha P. Crespo-Garcia S, et al. Among authors: fournier f. Nat Med. 2024 Feb;30(2):443-454. doi: 10.1038/s41591-024-02802-4. Epub 2024 Feb 6. Nat Med. 2024. PMID: 38321220 Clinical Trial.
Association between genome-wide epigenetic and genetic alterations in breast cancer tissue and response to HER2-targeted therapies in HER2-positive breast cancer patients: new findings and a systematic review.
Furrer D, Dragic D, Chang SL, Fournier F, Droit A, Jacob S, Diorio C. Furrer D, et al. Among authors: fournier f. Cancer Drug Resist. 2022 Nov 2;5(4):995-1015. doi: 10.20517/cdr.2022.63. eCollection 2022. Cancer Drug Resist. 2022. PMID: 36627894 Free PMC article. Review.
161 results