Fotovati A - Search Results

1

Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.

Lee C, Fotovati A, Triscott J, Chen J, Venugopal C, Singhal A, Dunham C, Kerr JM, Verreault M, Yip S, Wakimoto H, Jones C, Jayanthan A, Narendran A, Singh SK, Dunn SE. Lee C, et al. Among authors: fotovati a. Stem Cells. 2012 Jun;30(6):1064-75. doi: 10.1002/stem.1081. Stem Cells. 2012. PMID: 22415968

2

Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells.

Hu K, Law JH, Fotovati A, Dunn SE. Hu K, et al. Among authors: fotovati a. Breast Cancer Res. 2012 Feb 6;14(1):R22. doi: 10.1186/bcr3107. Breast Cancer Res. 2012. PMID: 22309939 Free PMC article.

3

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.

Triscott J, Lee C, Foster C, Manoranjan B, Pambid MR, Berns R, Fotovati A, Venugopal C, O'Halloran K, Narendran A, Hawkins C, Ramaswamy V, Bouffet E, Taylor MD, Singhal A, Hukin J, Rassekh R, Yip S, Northcott P, Singh SK, Dunham C, Dunn SE. Triscott J, et al. Among authors: fotovati a. Cancer Res. 2013 Nov 15;73(22):6734-44. doi: 10.1158/0008-5472.CAN-12-4331. Epub 2013 Sep 9. Cancer Res. 2013. PMID: 24019381

4

YB-1 bridges neural stem cells and brain tumor-initiating cells via its roles in differentiation and cell growth.

Fotovati A, Abu-Ali S, Wang PS, Deleyrolle LP, Lee C, Triscott J, Chen JY, Franciosi S, Nakamura Y, Sugita Y, Uchiumi T, Kuwano M, Leavitt BR, Singh SK, Jury A, Jones C, Wakimoto H, Reynolds BA, Pallen CJ, Dunn SE. Fotovati A, et al. Cancer Res. 2011 Aug 15;71(16):5569-78. doi: 10.1158/0008-5472.CAN-10-2805. Epub 2011 Jul 5. Cancer Res. 2011. PMID: 21730024

5

Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers.

Stratford AL, Reipas K, Hu K, Fotovati A, Brough R, Frankum J, Takhar M, Watson P, Ashworth A, Lord CJ, Lasham A, Print CG, Dunn SE. Stratford AL, et al. Among authors: fotovati a. Stem Cells. 2012 Jul;30(7):1338-48. doi: 10.1002/stem.1128. Stem Cells. 2012. PMID: 22674792

6

Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.

Triscott J, Lee C, Hu K, Fotovati A, Berns R, Pambid M, Luk M, Kast RE, Kong E, Toyota E, Yip S, Toyota B, Dunn SE. Triscott J, et al. Among authors: fotovati a. Oncotarget. 2012 Oct;3(10):1112-23. doi: 10.18632/oncotarget.604. Oncotarget. 2012. PMID: 23047041 Free PMC article.

7

YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer.

Davies AH, Reipas KM, Pambid MR, Berns R, Stratford AL, Fotovati A, Firmino N, Astanehe A, Hu K, Maxwell C, Mills GB, Dunn SE. Davies AH, et al. Among authors: fotovati a. Stem Cells. 2014 Jun;32(6):1437-50. doi: 10.1002/stem.1707. Stem Cells. 2014. PMID: 24648416 Free PMC article.

8

Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.

Hu K, Lee C, Qiu D, Fotovati A, Davies A, Abu-Ali S, Wai D, Lawlor ER, Triche TJ, Pallen CJ, Dunn SE. Hu K, et al. Among authors: fotovati a. Mol Cancer Ther. 2009 Nov;8(11):3024-35. doi: 10.1158/1535-7163.MCT-09-0365. Epub 2009 Nov 3. Mol Cancer Ther. 2009. PMID: 19887553 Free PMC article.

9

Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.

Gao Y, Fotovati A, Lee C, Wang M, Cote G, Guns E, Toyota B, Faury D, Jabado N, Dunn SE. Gao Y, et al. Among authors: fotovati a. Mol Cancer Ther. 2009 Dec;8(12):3276-84. doi: 10.1158/1535-7163.MCT-09-0478. Mol Cancer Ther. 2009. PMID: 19996271

10

MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition.

Astanehe A, Finkbeiner MR, Krzywinski M, Fotovati A, Dhillon J, Berquin IM, Mills GB, Marra MA, Dunn SE. Astanehe A, et al. Among authors: fotovati a. Oncogene. 2012 Oct 11;31(41):4434-46. doi: 10.1038/onc.2011.617. Epub 2012 Jan 16. Oncogene. 2012. PMID: 22249268

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

40 results

Search Page