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Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Among authors: fotie j. Bioorg Chem. 2021 Feb;107:104595. doi: 10.1016/j.bioorg.2020.104595. Epub 2020 Dec 30. Bioorg Chem. 2021. PMID: 33450548 Free PMC article.
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Among authors: fotie j. Data Brief. 2021 Feb 10;35:106858. doi: 10.1016/j.dib.2021.106858. eCollection 2021 Apr. Data Brief. 2021. PMID: 33665254 Free PMC article.
Unexpected 5,6,7,8,9,10-hexahydro-6,6-pentamethylenephenanthridines and 2,3,4,5-tetrahydro-4,4-tetramethylene-1H-cyclopenta[c]quinolines from Skraup-Doebner-Von Miller quinoline synthesis and their implications for the mechanism of that reaction.
Fotie J, Kemami Wangun HV, Fronczek FR, Massawe N, Bhattarai BT, Rhodus JL, Singleton TA, Bohle DS. Fotie J, et al. J Org Chem. 2012 Mar 16;77(6):2784-90. doi: 10.1021/jo202681r. Epub 2012 Feb 28. J Org Chem. 2012. PMID: 22335838
Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents.
George TG, Endeshaw MM, Morgan RE, Mahasenan KV, Delfín DA, Mukherjee MS, Yakovich AJ, Fotie J, Li C, Werbovetz KA. George TG, et al. Among authors: fotie j. Bioorg Med Chem. 2007 Sep 15;15(18):6071-9. doi: 10.1016/j.bmc.2007.06.042. Epub 2007 Jun 27. Bioorg Med Chem. 2007. PMID: 17618122 Free PMC article.
Inhibitors of tubulin assembly identified through screening a compound library.
Morgan RE, Ahn S, Nzimiro S, Fotie J, Phelps MA, Cotrill J, Yakovich AJ, Sackett DL, Dalton JT, Werbovetz KA. Morgan RE, et al. Among authors: fotie j. Chem Biol Drug Des. 2008 Dec;72(6):513-24. doi: 10.1111/j.1747-0285.2008.00729.x. Chem Biol Drug Des. 2008. PMID: 19090918 Free PMC article.
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