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Page 1
Analytical applications for pore-forming proteins.
Kasianowicz JJ, Balijepalli AK, Ettedgui J, Forstater JH, Wang H, Zhang H, Robertson JW. Kasianowicz JJ, et al. Among authors: forstater jh. Biochim Biophys Acta. 2016 Mar;1858(3):593-606. doi: 10.1016/j.bbamem.2015.09.023. Epub 2015 Oct 22. Biochim Biophys Acta. 2016. PMID: 26431785 Free article. Review.
Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454.
Benkovics T, Peng F, Phillips EM, An C, Bade RS, Chung CK, Dance ZEX, Fier PS, Forstater JH, Liu Z, Liu Z, Maligres PE, Marshall NM, Salehi Marzijarani N, McIntosh JA, Miller SP, Moore JC, Neel AJ, Obligacion JV, Pan W, Pirnot MT, Poirier M, Reibarkh M, Sherry BD, Song ZJ, Tan L, Turnbull BWH, Verma D, Waldman JH, Wang L, Wang T, Winston MS, Xu F. Benkovics T, et al. Among authors: forstater jh. J Am Chem Soc. 2022 Apr 6;144(13):5855-5863. doi: 10.1021/jacs.1c12106. Epub 2022 Mar 25. J Am Chem Soc. 2022. PMID: 35333525
A kinase-cGAS cascade to synthesize a therapeutic STING activator.
McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, Huffman MA, Miller SP, Tsay FR, Altman MD, Lesburg CA, Steinhuebel D, Trotter BW, Cumming JN, Northrup A, Bu X, Mann BF, Biba M, Hiraga K, Murphy GS, Kolev JN, Makarewicz A, Pan W, Farasat I, Bade RS, Stone K, Duan D, Alvizo O, Adpressa D, Guetschow E, Hoyt E, Regalado EL, Castro S, Rivera N, Smith JP, Wang F, Crespo A, Verma D, Axnanda S, Dance ZEX, Devine PN, Tschaen D, Canada KA, Bulger PG, Sherry BD, Truppo MD, Ruck RT, Campeau LC, Bennett DJ, Humphrey GR, Campos KR, Maddess ML. McIntosh JA, et al. Among authors: forstater jh. Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16. Nature. 2022. PMID: 35296845
Design of an in vitro biocatalytic cascade for the manufacture of islatravir.
Huffman MA, Fryszkowska A, Alvizo O, Borra-Garske M, Campos KR, Canada KA, Devine PN, Duan D, Forstater JH, Grosser ST, Halsey HM, Hughes GJ, Jo J, Joyce LA, Kolev JN, Liang J, Maloney KM, Mann BF, Marshall NM, McLaughlin M, Moore JC, Murphy GS, Nawrat CC, Nazor J, Novick S, Patel NR, Rodriguez-Granillo A, Robaire SA, Sherer EC, Truppo MD, Whittaker AM, Verma D, Xiao L, Xu Y, Yang H. Huffman MA, et al. Among authors: forstater jh. Science. 2019 Dec 6;366(6470):1255-1259. doi: 10.1126/science.aay8484. Science. 2019. PMID: 31806816