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Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.
Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12466-12471. doi: 10.1073/pnas.1713085114. Epub 2017 Nov 6.
Proc Natl Acad Sci U S A. 2017.
PMID: 29109257
Free PMC article.
Oxidative DNA damage stalls the human mitochondrial replisome.
Stojkovič G, Makarova AV, Wanrooij PH, Forslund J, Burgers PM, Wanrooij S.
Stojkovič G, et al.
Sci Rep. 2016 Jul 1;6:28942. doi: 10.1038/srep28942.
Sci Rep. 2016.
PMID: 27364318
Free PMC article.
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PrimPol is required for replication reinitiation after mtDNA damage.
Torregrosa-Muñumer R, Forslund JME, Goffart S, Pfeiffer A, Stojkovič G, Carvalho G, Al-Furoukh N, Blanco L, Wanrooij S, Pohjoismäki JLO.
Torregrosa-Muñumer R, et al. Among authors: forslund jme.
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11398-11403. doi: 10.1073/pnas.1705367114. Epub 2017 Oct 9.
Proc Natl Acad Sci U S A. 2017.
PMID: 29073063
Free PMC article.
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The presence of rNTPs decreases the speed of mitochondrial DNA replication.
Forslund JME, Pfeiffer A, Stojkovič G, Wanrooij PH, Wanrooij S.
Forslund JME, et al.
PLoS Genet. 2018 Mar 30;14(3):e1007315. doi: 10.1371/journal.pgen.1007315. eCollection 2018 Mar.
PLoS Genet. 2018.
PMID: 29601571
Free PMC article.
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Known Unknowns of Mammalian Mitochondrial DNA Maintenance.
Pohjoismäki JLO, Forslund JME, Goffart S, Torregrosa-Muñumer R, Wanrooij S.
Pohjoismäki JLO, et al. Among authors: forslund jme.
Bioessays. 2018 Sep;40(9):e1800102. doi: 10.1002/bies.201800102. Epub 2018 Jul 12.
Bioessays. 2018.
PMID: 29999547
Review.
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Rolling Circle Replication and Bypass of Damaged Nucleotides.
Forslund JME, Stojkovič G, Wanrooij S.
Forslund JME, et al.
Methods Mol Biol. 2023;2615:203-217. doi: 10.1007/978-1-0716-2922-2_15.
Methods Mol Biol. 2023.
PMID: 36807794
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