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Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: forslund jme. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12466-12471. doi: 10.1073/pnas.1713085114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109257 Free PMC article.
PrimPol is required for replication reinitiation after mtDNA damage.
Torregrosa-Muñumer R, Forslund JME, Goffart S, Pfeiffer A, Stojkovič G, Carvalho G, Al-Furoukh N, Blanco L, Wanrooij S, Pohjoismäki JLO. Torregrosa-Muñumer R, et al. Among authors: forslund jme. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11398-11403. doi: 10.1073/pnas.1705367114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073063 Free PMC article.
Known Unknowns of Mammalian Mitochondrial DNA Maintenance.
Pohjoismäki JLO, Forslund JME, Goffart S, Torregrosa-Muñumer R, Wanrooij S. Pohjoismäki JLO, et al. Among authors: forslund jme. Bioessays. 2018 Sep;40(9):e1800102. doi: 10.1002/bies.201800102. Epub 2018 Jul 12. Bioessays. 2018. PMID: 29999547 Review.