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A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Chang D, Hunkapiller J, Bhangale T, Reeder J, Mukhyala K, Tom J, Cowgill A, Vogel J, Forrest WF, Khan Z, Stockwell A, McCarthy MI, Staton TL, Olsson J, Holweg CTJ, Cheung DS, Chen H, Brauer MJ, Graham RR, Behrens T, Wilson MS, Arron JR, Choy DF, Yaspan BL. Chang D, et al. Among authors: forrest wf. Sci Rep. 2022 Apr 2;12(1):5574. doi: 10.1038/s41598-022-09447-8. Sci Rep. 2022. PMID: 35368043 Free PMC article.
Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms.
Haug-Baltzell A, Bhangale TR, Chang D, Dressen A, Yaspan BL, Ortmann W, Brauer MJ, Hunkapiller J, Reeder J, Mukhyala K, Cuenco KT, Tom JA, Cowgill A, Vogel J, Forrest WF, Behrens TW, Graham RR, Wuster A. Haug-Baltzell A, et al. Among authors: forrest wf. Genes Immun. 2019 Feb;20(2):172-179. doi: 10.1038/s41435-018-0018-z. Epub 2018 Mar 18. Genes Immun. 2019. PMID: 29550837 Free PMC article.
Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study.
Dressen A, Abbas AR, Cabanski C, Reeder J, Ramalingam TR, Neighbors M, Bhangale TR, Brauer MJ, Hunkapiller J, Reeder J, Mukhyala K, Cuenco K, Tom J, Cowgill A, Vogel J, Forrest WF, Collard HR, Wolters PJ, Kropski JA, Lancaster LH, Blackwell TS, Arron JR, Yaspan BL. Dressen A, et al. Among authors: forrest wf. Lancet Respir Med. 2018 Aug;6(8):603-614. doi: 10.1016/S2213-2600(18)30135-8. Epub 2018 Jun 18. Lancet Respir Med. 2018. PMID: 29891356 Free PMC article.
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration.
Lim YW, Chen-Harris H, Mayba O, Lianoglou S, Wuster A, Bhangale T, Khan Z, Mariathasan S, Daemen A, Reeder J, Haverty PM, Forrest WF, Brauer M, Mellman I, Albert ML. Lim YW, et al. Among authors: forrest wf. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11701-E11710. doi: 10.1073/pnas.1804506115. Epub 2018 Nov 21. Proc Natl Acad Sci U S A. 2018. PMID: 30463956 Free PMC article.
Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity.
Weber M, Min SW, Truong T, Hung J, Dale S, Reichelt M, Ubhayakar S, Cain-Hom C, Baca M, Jiang Z, Li Q, Brendza R, Lin H, Kung C, Forrest WF, Quiason-Huynh C, Sandoval W, Chen B, Deng Y, Easton A, Foreman O, Sene A, Bingol B. Weber M, et al. Among authors: forrest wf. Sci Rep. 2021 Mar 16;11(1):6079. doi: 10.1038/s41598-021-85528-4. Sci Rep. 2021. PMID: 33727605 Free PMC article.
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema.
Stockwell AD, Chang MC, Mahajan A, Forrest W, Anegondi N, Pendergrass RK, Selvaraj S, Reeder J, Wei E, Iglesias VA, Creps NM, Macri L, Neeranjan AN, van der Brug MP, Scales SJ, McCarthy MI, Yaspan BL. Stockwell AD, et al. PLoS Genet. 2023 Aug 16;19(8):e1010609. doi: 10.1371/journal.pgen.1010609. eCollection 2023 Aug. PLoS Genet. 2023. PMID: 37585454 Free PMC article.
61 results