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Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.
Cantoni D, Murray MJ, Kalemera MD, Dicken SJ, Stejskal L, Brown G, Lytras S, Coey JD, McKenna J, Bridgett S, Simpson D, Fairley D, Thorne LG, Reuschl AK, Forrest C, Ganeshalingham M, Muir L, Palor M, Jarvis L, Willett B, Power UF, McCoy LE, Jolly C, Towers GJ, Doores KJ, Robertson DL, Shepherd AJ, Reeves MB, Bamford CGG, Grove J. Cantoni D, et al. Among authors: forrest c. EMBO Rep. 2022 Oct 6;23(10):e54322. doi: 10.15252/embr.202154322. Epub 2022 Sep 1. EMBO Rep. 2022. PMID: 35999696 Free PMC article.
Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.
Dicken SJ, Murray MJ, Thorne LG, Reuschl AK, Forrest C, Ganeshalingham M, Muir L, Kalemera MD, Palor M, McCoy LE, Jolly C, Towers GJ, Reeves MB, Grove J. Dicken SJ, et al. Among authors: forrest c. bioRxiv [Preprint]. 2021 Mar 22:2021.03.22.436468. doi: 10.1101/2021.03.22.436468. bioRxiv. 2021. PMID: 33791702 Free PMC article. Preprint.
Redirection to the bone marrow improves T cell persistence and antitumor functions.
Khan AB, Carpenter B, Santos E Sousa P, Pospori C, Khorshed R, Griffin J, Velica P, Zech M, Ghorashian S, Forrest C, Thomas S, Gonzalez Anton S, Ahmadi M, Holler A, Flutter B, Ramirez-Ortiz Z, Means TK, Bennett CL, Stauss H, Morris E, Lo Celso C, Chakraverty R. Khan AB, et al. Among authors: forrest c. J Clin Invest. 2018 May 1;128(5):2010-2024. doi: 10.1172/JCI97454. Epub 2018 Apr 9. J Clin Invest. 2018. PMID: 29485974 Free PMC article.
Persistent low-level variants in a subset of viral genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infection.
Venturini C, Colston JM, Charles O, Lankina A, Best T, Atkinson C, Forrest C, Williams CA, Rao K, Worth A, Thorburn D, Harber M, Griffiths P, Breuer J. Venturini C, et al. Among authors: forrest c. J Infect Dis. 2024 Jan 5:jiae001. doi: 10.1093/infdis/jiae001. Online ahead of print. J Infect Dis. 2024. PMID: 38181168
715 results