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Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential.
Carlessi R, Denisenko E, Boslem E, Köhn-Gaone J, Main N, Abu Bakar NDB, Shirolkar GD, Jones M, Beasley AB, Poppe D, Dwyer BJ, Jackaman C, Tjiam MC, Lister R, Karin M, Fallowfield JA, Kendall TJ, Forbes SJ, Gray ES, Olynyk JK, Yeoh G, Forrest ARR, Ramm GA, Febbraio MA, Tirnitz-Parker JEE. Carlessi R, et al. Among authors: forrest arr. Cell Genom. 2023 Apr 13;3(5):100301. doi: 10.1016/j.xgen.2023.100301. eCollection 2023 May 10. Cell Genom. 2023. PMID: 37228755 Free PMC article.
Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution.
Cabanes-Creus M, Navarro RG, Liao SHY, Scott S, Carlessi R, Roca-Pinilla R, Knight M, Baltazar G, Zhu E, Jones M, Denisenko E, Forrest ARR, Alexander IE, Tirnitz-Parker JEE, Lisowski L. Cabanes-Creus M, et al. Among authors: forrest arr. Mol Ther Methods Clin Dev. 2023 Jan 2;28:220-237. doi: 10.1016/j.omtm.2022.12.014. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2023. PMID: 36700121 Free PMC article.
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution.
Herring CA, Simmons RK, Freytag S, Poppe D, Moffet JJD, Pflueger J, Buckberry S, Vargas-Landin DB, Clément O, Echeverría EG, Sutton GJ, Alvarez-Franco A, Hou R, Pflueger C, McDonald K, Polo JM, Forrest ARR, Nowak AK, Voineagu I, Martelotto L, Lister R. Herring CA, et al. Among authors: forrest arr. Cell. 2022 Nov 10;185(23):4428-4447.e28. doi: 10.1016/j.cell.2022.09.039. Epub 2022 Oct 31. Cell. 2022. PMID: 36318921 Free article.
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes.
Kidman J, Zemek RM, Sidhom JW, Correa D, Principe N, Sheikh F, Fear VS, Forbes CA, Chopra A, Boon L, Zaitouny A, de Jong E, Holt RA, Jones M, Millward MJ, Lassmann T, Forrest ARR, Nowak AK, Watson M, Lake RA, Lesterhuis WJ, Chee J. Kidman J, et al. Among authors: forrest arr. Oncoimmunology. 2024 Apr 26;13(1):2345859. doi: 10.1080/2162402X.2024.2345859. eCollection 2024. Oncoimmunology. 2024. PMID: 38686178 Free PMC article.
Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones.
Denisenko E, de Kock L, Tan A, Beasley AB, Beilin M, Jones ME, Hou R, Muirí DÓ, Bilic S, Mohan GRKA, Salfinger S, Fox S, Hmon KPW, Yeow Y, Kim Y, John R, Gilderman TS, Killingbeck E, Gray ES, Cohen PA, Yu Y, Forrest ARR. Denisenko E, et al. Among authors: forrest arr. Nat Commun. 2024 Apr 3;15(1):2860. doi: 10.1038/s41467-024-47271-y. Nat Commun. 2024. PMID: 38570491 Free PMC article.
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.
Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan CL, McLennan E, Terry LV, Nobis M, Mu A, Nowell C, Horadagoda N, Henstridge DC, Mellett NA, Timpson P, Jones M, Denisenko E, Forrest ARR, Tirnitz-Parker JEE, Meikle PJ, Rose-John S, Karin M, Febbraio MA. Boslem E, et al. Among authors: forrest arr. Sci Adv. 2023 Sep 15;9(37):eadh0831. doi: 10.1126/sciadv.adh0831. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703359 Free PMC article.
133 results