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Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. Forner S, et al. Sci Data. 2021 Oct 15;8(1):270. doi: 10.1038/s41597-021-01054-y. Sci Data. 2021. PMID: 34654824 Free PMC article.
Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease.
Baglietto-Vargas D, Prieto GA, Limon A, Forner S, Rodriguez-Ortiz CJ, Ikemura K, Ager RR, Medeiros R, Trujillo-Estrada L, Martini AC, Kitazawa M, Davila JC, Cotman CW, Gutierrez A, LaFerla FM. Baglietto-Vargas D, et al. Among authors: forner s. Aging Cell. 2018 Aug;17(4):e12791. doi: 10.1111/acel.12791. Epub 2018 Jun 6. Aging Cell. 2018. PMID: 29877034 Free PMC article.
Astrocytes: From the Physiology to the Disease.
Trujillo-Estrada L, Gomez-Arboledas A, Forner S, Martini AC, Gutierrez A, Baglietto-Vargas D, LaFerla FM. Trujillo-Estrada L, et al. Among authors: forner s. Curr Alzheimer Res. 2019;16(8):675-698. doi: 10.2174/1567205016666190830110152. Curr Alzheimer Res. 2019. PMID: 31470787 Review.
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling.
Martini AC, Gomez-Arboledas A, Forner S, Rodriguez-Ortiz CJ, McQuade A, Danhash E, Phan J, Javonillo D, Ha JV, Tram M, Trujillo-Estrada L, da Cunha C, Ager RR, Davila JC, Kitazawa M, Blurton-Jones M, Gutierrez A, Baglietto-Vargas D, Medeiros R, LaFerla FM. Martini AC, et al. Among authors: forner s. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21198-21206. doi: 10.1073/pnas.1914088116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570577 Free PMC article.
Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus.
Forner S, Martini AC, Prieto GA, Dang CT, Rodriguez-Ortiz CJ, Reyes-Ruiz JM, Trujillo-Estrada L, da Cunha C, Andrews EJ, Phan J, Vu Ha J, Chang AVZD, Levites Y, Cruz PE, Ager R, Medeiros R, Kitazawa M, Glabe CG, Cotman CW, Golde T, Baglietto-Vargas D, LaFerla FM. Forner S, et al. Sci Rep. 2019 Nov 4;9(1):15936. doi: 10.1038/s41598-019-52324-0. Sci Rep. 2019. PMID: 31685865 Free PMC article.
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Rodriguez-Ortiz CJ, Prieto GA, Martini AC, Forner S, Trujillo-Estrada L, LaFerla FM, Baglietto-Vargas D, Cotman CW, Kitazawa M. Rodriguez-Ortiz CJ, et al. Among authors: forner s. Aging Cell. 2020 Mar;19(3):e13118. doi: 10.1111/acel.13118. Epub 2020 Feb 22. Aging Cell. 2020. PMID: 32087004 Free PMC article.
Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD.
Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, LaFerla FM, Lamb BT; and The MODEL‐AD; Consortium. Oblak AL, et al. Among authors: forner s. Alzheimers Dement (N Y). 2020 Nov 23;6(1):e12110. doi: 10.1002/trc2.12110. eCollection 2020. Alzheimers Dement (N Y). 2020. PMID: 33283040 Free PMC article.
54 results