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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells.
Wang Z, McWilliams-Koeppen HP, Reza H, Ostberg JR, Chen W, Wang X, Huynh C, Vyas V, Chang WC, Starr R, Wagner JR, Aguilar B, Yang X, Wu X, Wang J, Chen W, Koelker-Wolfe E, Seet CS, Montel-Hagen A, Crooks GM, Forman SJ, Brown CE. Wang Z, et al. Among authors: forman sj. Cell Stem Cell. 2022 Apr 7;29(4):515-527.e8. doi: 10.1016/j.stem.2022.02.009. Epub 2022 Mar 11. Cell Stem Cell. 2022. PMID: 35278370 Free PMC article.
T-cell genetic modification for re-directed tumor recognition.
Cooper LJ, Kalos M, DiGiusto D, Brown C, Forman SJ, Raubitschek A, Jensen MC. Cooper LJ, et al. Among authors: forman sj. Cancer Chemother Biol Response Modif. 2005;22:293-324. doi: 10.1016/s0921-4410(04)22014-2. Cancer Chemother Biol Response Modif. 2005. PMID: 16110618 Review. No abstract available.
Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans.
Jensen MC, Popplewell L, Cooper LJ, DiGiusto D, Kalos M, Ostberg JR, Forman SJ. Jensen MC, et al. Among authors: forman sj. Biol Blood Marrow Transplant. 2010 Sep;16(9):1245-56. doi: 10.1016/j.bbmt.2010.03.014. Epub 2010 Mar 19. Biol Blood Marrow Transplant. 2010. PMID: 20304086 Free PMC article. Clinical Trial.
651 results