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Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.
Eur J Med Chem. 2018 Mar 10;147:130-149. doi: 10.1016/j.ejmech.2018.01.094. Epub 2018 Feb 2.
Eur J Med Chem. 2018.
PMID: 29427906
Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells.
Shayhidin EE, Forcellini E, Boulanger MC, Mahmut A, Dautrey S, Barbeau X, Lagüe P, Sévigny J, Paquin JF, Mathieu P.
Shayhidin EE, et al. Among authors: forcellini e.
Br J Pharmacol. 2015 Aug;172(16):4189-99. doi: 10.1111/bph.13204. Epub 2015 Jul 8.
Br J Pharmacol. 2015.
PMID: 26031197
Free PMC article.
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Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity.
Lefebvre CA, Forcellini E, Boutin S, Côté MF, C-Gaudreault R, Mathieu P, Lagüe P, Paquin JF.
Lefebvre CA, et al. Among authors: forcellini e.
Bioorg Med Chem Lett. 2017 Jan 15;27(2):299-302. doi: 10.1016/j.bmcl.2016.11.052. Epub 2016 Nov 19.
Bioorg Med Chem Lett. 2017.
PMID: 27903409
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Synthesis and pharmacological evaluation of a new series of radiolabeled ligands for 5-HT7 receptor PET neuroimaging.
Colomb J, Becker G, Forcellini E, Meyer S, Buisson L, Zimmer L, Billard T.
Colomb J, et al. Among authors: forcellini e.
Nucl Med Biol. 2014 Apr;41(4):330-7. doi: 10.1016/j.nucmedbio.2014.01.008. Epub 2014 Jan 17.
Nucl Med Biol. 2014.
PMID: 24607435
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