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The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice.
Lanterna C, Musumeci A, Raccosta L, Corna G, Moresco M, Maggioni D, Fontana R, Doglioni C, Bordignon C, Traversari C, Russo V. Lanterna C, et al. Among authors: fontana r. Cancer Immunol Immunother. 2016 Nov;65(11):1303-1315. doi: 10.1007/s00262-016-1884-8. Epub 2016 Aug 12. Cancer Immunol Immunother. 2016. PMID: 27520505 Free PMC article.
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses.
Villablanca EJ, Raccosta L, Zhou D, Fontana R, Maggioni D, Negro A, Sanvito F, Ponzoni M, Valentinis B, Bregni M, Prinetti A, Steffensen KR, Sonnino S, Gustafsson JA, Doglioni C, Bordignon C, Traversari C, Russo V. Villablanca EJ, et al. Among authors: fontana r. Nat Med. 2010 Jan;16(1):98-105. doi: 10.1038/nm.2074. Epub 2009 Dec 27. Nat Med. 2010. PMID: 20037595
Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors.
Fontana R, Raccosta L, Rovati L, Steffensen KR, Paniccia A, Jakobsson T, Melloni G, Bandiera A, Mangili G, Bergamini A, Maggioni D, Doglioni C, Crocchiolo R, Cella M, Mattioli M, Battaglia C, Colonna M, Russo V. Fontana R, et al. Oncoimmunology. 2018 Dec 13;8(3):1554967. doi: 10.1080/2162402X.2018.1554967. eCollection 2019. Oncoimmunology. 2018. PMID: 30723587 Free PMC article.
904 results