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Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment.
Su X, Xu Y, Fox GC, Xiang J, Kwakwa KA, Davis JL, Belle JI, Lee WC, Wong WH, Fontana F, Hernandez-Aya LF, Kobayashi T, Tomasson HM, Su J, Bakewell SJ, Stewart SA, Egbulefu C, Karmakar P, Meyer MA, Veis DJ, DeNardo DG, Lanza GM, Achilefu S, Weilbaecher KN. Su X, et al. Among authors: fontana f. J Clin Invest. 2021 Oct 15;131(20):e145296. doi: 10.1172/JCI145296. J Clin Invest. 2021. PMID: 34520398 Free PMC article.
CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.
Xiang J, Hurchla MA, Fontana F, Su X, Amend SR, Esser AK, Douglas GJ, Mudalagiriyappa C, Luker KE, Pluard T, Ademuyiwa FO, Romagnoli B, Tuffin G, Chevalier E, Luker GD, Bauer M, Zimmermann J, Aft RL, Dembowsky K, Weilbaecher KN. Xiang J, et al. Among authors: fontana f. Mol Cancer Ther. 2015 Nov;14(11):2473-85. doi: 10.1158/1535-7163.MCT-15-0252. Epub 2015 Aug 12. Mol Cancer Ther. 2015. PMID: 26269605 Free PMC article.
Antagonizing Integrin β3 Increases Immunosuppression in Cancer.
Su X, Esser AK, Amend SR, Xiang J, Xu Y, Ross MH, Fox GC, Kobayashi T, Steri V, Roomp K, Fontana F, Hurchla MA, Knolhoff BL, Meyer MA, Morgan EA, Tomasson JC, Novack JS, Zou W, Faccio R, Novack DV, Robinson SD, Teitelbaum SL, DeNardo DG, Schneider JG, Weilbaecher KN. Su X, et al. Among authors: fontana f. Cancer Res. 2016 Jun 15;76(12):3484-95. doi: 10.1158/0008-5472.CAN-15-2663. Epub 2016 May 23. Cancer Res. 2016. PMID: 27216180 Free PMC article.
Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.
Fontana F, Ge X, Su X, Hathi D, Xiang J, Cenci S, Civitelli R, Shoghi KI, Akers WJ, D'avignon A, Weilbaecher KN, Shokeen M. Fontana F, et al. Clin Cancer Res. 2017 Jan 15;23(2):416-429. doi: 10.1158/1078-0432.CCR-15-2134. Epub 2016 Aug 2. Clin Cancer Res. 2017. PMID: 27486177 Free PMC article.
HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia.
Xiang J, Rauch DA, Huey DD, Panfil AR, Cheng X, Esser AK, Su X, Harding JC, Xu Y, Fox GC, Fontana F, Kobayashi T, Su J, Sundaramoorthi H, Wong WH, Jia Y, Rosol TJ, Veis DJ, Green PL, Niewiesk S, Ratner L, Weilbaecher KN. Xiang J, et al. Among authors: fontana f. JCI Insight. 2019 Oct 3;4(19):e128713. doi: 10.1172/jci.insight.128713. JCI Insight. 2019. PMID: 31578308 Free PMC article.
Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer.
Esser AK, Ross MH, Fontana F, Su X, Gabay A, Fox GC, Xu Y, Xiang J, Schmieder AH, Yang X, Cui G, Scott M, Achilefu S, Chauhan J, Fletcher S, Lanza GM, Weilbaecher KN. Esser AK, et al. Among authors: fontana f. Theranostics. 2020 Jun 12;10(17):7510-7526. doi: 10.7150/thno.44523. eCollection 2020. Theranostics. 2020. PMID: 32685002 Free PMC article.
VLA4-Targeted Nanoparticles Hijack Cell Adhesion-Mediated Drug Resistance to Target Refractory Myeloma Cells and Prolong Survival.
Fontana F, Scott MJ, Allen JS, Yang X, Cui G, Pan D, Yanaba N, Fiala MA, O'Neal J, Schmieder-Atteberry AH, Ritchey J, Rettig M, Simons K, Fletcher S, Vij R, DiPersio JF, Lanza GM. Fontana F, et al. Clin Cancer Res. 2021 Apr 1;27(7):1974-1986. doi: 10.1158/1078-0432.CCR-20-2839. Epub 2020 Dec 22. Clin Cancer Res. 2021. PMID: 33355244 Free PMC article.
Targeted Therapy to β3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases.
Fox GC, Su X, Davis JL, Xu Y, Kwakwa KA, Ross MH, Fontana F, Xiang J, Esser AK, Cordell E, Pagliai K, Dang HX, Sivapackiam J, Stewart SA, Maher CA, Bakewell SJ, Fitzpatrick JAJ, Sharma V, Achilefu S, Veis DJ, Lanza GM, Weilbaecher KN. Fox GC, et al. Among authors: fontana f. Mol Cancer Ther. 2021 Jun;20(6):1183-1198. doi: 10.1158/1535-7163.MCT-20-0931. Epub 2021 Mar 30. Mol Cancer Ther. 2021. PMID: 33785647 Free PMC article.
740 results