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Control of Neurotransmission by NaV1.7 in Human, Guinea Pig, and Mouse Airway Parasympathetic Nerves.
Kocmalova M, Kollarik M, Canning BJ, Ru F, Adam Herbstsomer R, Meeker S, Fonquerna S, Aparici M, Miralpeix M, Chi XX, Li B, Wilenkin B, McDermott J, Nisenbaum E, Krajewski JL, Undem BJ. Kocmalova M, et al. Among authors: fonquerna s. J Pharmacol Exp Ther. 2017 Apr;361(1):172-180. doi: 10.1124/jpet.116.238469. Epub 2017 Jan 30. J Pharmacol Exp Ther. 2017. PMID: 28138042 Free PMC article.
Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.
Planagumà A, Domènech T, Pont M, Calama E, García-González V, López R, Aulí M, López M, Fonquerna S, Ramos I, de Alba J, Nueda A, Prats N, Segarra V, Miralpeix M, Lehner MD. Planagumà A, et al. Among authors: fonquerna s. Pulm Pharmacol Ther. 2015 Oct;34:37-45. doi: 10.1016/j.pupt.2015.08.002. Epub 2015 Aug 10. Pulm Pharmacol Ther. 2015. PMID: 26271598 Review.
Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist.
Eastwood P, Esteve C, González J, Fonquerna S, Aiguadé J, Carranco I, Doménech T, Aparici M, Miralpeix M, Albertí J, Córdoba M, Fernández R, Pont M, Godessart N, Prats N, Loza MI, Cadavid MI, Nueda A, Vidal B. Eastwood P, et al. Among authors: fonquerna s. ACS Med Chem Lett. 2010 Dec 20;2(3):213-8. doi: 10.1021/ml100249e. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900298 Free PMC article.
Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.
Bach J, Eastwood P, González J, Gómez E, Alonso JA, Fonquerna S, Lozoya E, Orellana A, Maldonado M, Calaf E, Albertí J, Pérez J, Andrés A, Prats N, Carreño C, Calama E, De Alba J, Calbet M, Miralpeix M, Ramis I. Bach J, et al. Among authors: fonquerna s. J Med Chem. 2019 Oct 24;62(20):9045-9060. doi: 10.1021/acs.jmedchem.9b00533. Epub 2019 Oct 14. J Med Chem. 2019. PMID: 31609613