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Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation.
Miao W, Porter DF, Lopez-Pajares V, Siprashvili Z, Meyers RM, Bai Y, Nguyen DT, Ko LA, Zarnegar BJ, Ferguson ID, Mills MM, Jilly-Rehak CE, Wu CG, Yang YY, Meyers JM, Hong AW, Reynolds DL, Ramanathan M, Tao S, Jiang S, Flynn RA, Wang Y, Nolan GP, Khavari PA. Miao W, et al. Among authors: flynn ra. Cell. 2023 Jan 5;186(1):80-97.e26. doi: 10.1016/j.cell.2022.12.004. Cell. 2023. PMID: 36608661 Free PMC article.
Control of somatic tissue differentiation by the long non-coding RNA TINCR.
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA. Kretz M, et al. Among authors: flynn ra. Nature. 2013 Jan 10;493(7431):231-5. doi: 10.1038/nature11661. Epub 2012 Dec 2. Nature. 2013. PMID: 23201690 Free PMC article.
Dissecting noncoding and pathogen RNA-protein interactomes.
Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Flynn RA, et al. RNA. 2015 Jan;21(1):135-43. doi: 10.1261/rna.047803.114. Epub 2014 Nov 19. RNA. 2015. PMID: 25411354 Free PMC article.
7SK-BAF axis controls pervasive transcription at enhancers.
Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. Flynn RA, et al. Nat Struct Mol Biol. 2016 Mar;23(3):231-8. doi: 10.1038/nsmb.3176. Epub 2016 Feb 15. Nat Struct Mol Biol. 2016. PMID: 26878240 Free PMC article.
HiChIRP reveals RNA-associated chromosome conformation.
Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, Artandi SE, Fitzgerald KA, Greenleaf WJ, Chang HY. Mumbach MR, et al. Among authors: flynn ra. Nat Methods. 2019 Jun;16(6):489-492. doi: 10.1038/s41592-019-0407-x. Epub 2019 May 27. Nat Methods. 2019. PMID: 31133759 Free PMC article.
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells.
Santoriello C, Sporrij A, Yang S, Flynn RA, Henriques T, Dorjsuren B, Custo Greig E, McCall W, Stanhope ME, Fazio M, Superdock M, Lichtig A, Adatto I, Abraham BJ, Kalocsay M, Jurynec M, Zhou Y, Adelman K, Calo E, Zon LI. Santoriello C, et al. Among authors: flynn ra. Nat Cell Biol. 2020 Apr;22(4):372-379. doi: 10.1038/s41556-020-0493-0. Epub 2020 Mar 30. Nat Cell Biol. 2020. PMID: 32231306 Free PMC article.
c-Myc regulates transcriptional pause release.
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA. Rahl PB, et al. Among authors: flynn ra. Cell. 2010 Apr 30;141(3):432-45. doi: 10.1016/j.cell.2010.03.030. Cell. 2010. PMID: 20434984 Free PMC article.
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