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It's reticulated: the liver at the heart of atherosclerosis.
Nagareddy PR, Noothi SK, Flynn MC, Murphy AJ. Nagareddy PR, et al. Among authors: flynn mc. J Endocrinol. 2018 Jul;238(1):R1-R11. doi: 10.1530/JOE-18-0082. Epub 2018 May 2. J Endocrinol. 2018. PMID: 29720539 Free PMC article. Review.
Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.
Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: flynn mc. Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119. Eur Heart J. 2018. PMID: 29905812 Free PMC article.
Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16- Monocytes.
Lee MKS, Al-Sharea A, Shihata WA, Bertuzzo Veiga C, Cooney OD, Fleetwood AJ, Flynn MC, Claeson E, Palmer CS, Lancaster GI, Henstridge DC, Hamilton JA, Murphy AJ. Lee MKS, et al. Among authors: flynn mc. Front Immunol. 2019 Sep 6;10:2054. doi: 10.3389/fimmu.2019.02054. eCollection 2019. Front Immunol. 2019. PMID: 31555280 Free PMC article.
Fat for fuel: lipid metabolism in haematopoiesis.
Pernes G, Flynn MC, Lancaster GI, Murphy AJ. Pernes G, et al. Among authors: flynn mc. Clin Transl Immunology. 2019 Dec 24;8(12):e1098. doi: 10.1002/cti2.1098. eCollection 2019. Clin Transl Immunology. 2019. PMID: 31890207 Free PMC article. Review.
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis.
Flynn MC, Kraakman MJ, Tikellis C, Lee MKS, Hanssen NMJ, Kammoun HL, Pickering RJ, Dragoljevic D, Al-Sharea A, Barrett TJ, Hortle F, Byrne FL, Olzomer E, McCarthy DA, Schalkwijk CG, Forbes JM, Hoehn K, Makowski L, Lancaster GI, El-Osta A, Fisher EA, Goldberg IJ, Cooper ME, Nagareddy PR, Thomas MC, Murphy AJ. Flynn MC, et al. Circ Res. 2020 Sep 11;127(7):877-892. doi: 10.1161/CIRCRESAHA.120.316653. Epub 2020 Jun 22. Circ Res. 2020. PMID: 32564710 Free PMC article.
Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes.
Lee MKS, Kraakman MJ, Dragoljevic D, Hanssen NMJ, Flynn MC, Al-Sharea A, Sreejit G, Bertuzzo-Veiga C, Cooney OD, Baig F, Morriss E, Cooper ME, Josefsson EC, Kile BT, Nagareddy PR, Murphy AJ. Lee MKS, et al. Among authors: flynn mc. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1167-1178. doi: 10.1161/ATVBAHA.120.315369. Epub 2021 Jan 14. Arterioscler Thromb Vasc Biol. 2021. PMID: 33441028 Free PMC article.
Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.
Kraakman MJ, Lee MK, Al-Sharea A, Dragoljevic D, Barrett TJ, Montenont E, Basu D, Heywood S, Kammoun HL, Flynn M, Whillas A, Hanssen NM, Febbraio MA, Westein E, Fisher EA, Chin-Dusting J, Cooper ME, Berger JS, Goldberg IJ, Nagareddy PR, Murphy AJ. Kraakman MJ, et al. J Clin Invest. 2017 Jun 1;127(6):2133-2147. doi: 10.1172/JCI92450. Epub 2017 May 15. J Clin Invest. 2017. PMID: 28504650 Free PMC article.
65 results