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Mutational fitness landscape and drug resistance.
Flynn J, Samant N, Schneider-Nachum G, Tenzin T, Bolon DNA. Flynn J, et al. Curr Opin Struct Biol. 2023 Feb;78:102525. doi: 10.1016/j.sbi.2022.102525. Epub 2023 Jan 6. Curr Opin Struct Biol. 2023. PMID: 36621152 Free PMC article. Review.
Sculpting the proteome with AAA(+) proteases and disassembly machines.
Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA, Hersch GL, Joshi SA, Kenniston JA, Levchenko I, Neher SB, Oakes ES, Siddiqui SM, Wah DA, Baker TA. Sauer RT, et al. Cell. 2004 Oct 1;119(1):9-18. doi: 10.1016/j.cell.2004.09.020. Cell. 2004. PMID: 15454077 Free PMC article. Review.
Viewing protein fitness landscapes through a next-gen lens.
Boucher JI, Cote P, Flynn J, Jiang L, Laban A, Mishra P, Roscoe BP, Bolon DN. Boucher JI, et al. Among authors: flynn j. Genetics. 2014 Oct;198(2):461-71. doi: 10.1534/genetics.114.168351. Genetics. 2014. PMID: 25316787 Free PMC article. Review.
Mechanistic Asymmetry in Hsp90 Dimers.
Flynn JM, Mishra P, Bolon DN. Flynn JM, et al. J Mol Biol. 2015 Sep 11;427(18):2904-11. doi: 10.1016/j.jmb.2015.03.017. Epub 2015 Apr 3. J Mol Biol. 2015. PMID: 25843003 Free PMC article. Review.
The Adaptive Potential of the Middle Domain of Yeast Hsp90.
Cote-Hammarlof PA, Fragata I, Flynn J, Mavor D, Zeldovich KB, Bank C, Bolon DNA. Cote-Hammarlof PA, et al. Among authors: flynn j. Mol Biol Evol. 2021 Jan 23;38(2):368-379. doi: 10.1093/molbev/msaa211. Mol Biol Evol. 2021. PMID: 32871012 Free PMC article.
2,594 results