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A phase 1/2 study of lenalidomide and obinutuzumab with CHOP for newly diagnosed DLBCL.
Cherng HJ, Alig SK, Oki Y, Nastoupil LJ, Fayad L, Neelapu SS, Turturro F, Hagemeister F, Craig AFM, Macaulay CW, Rodriguez MA, Lee HJ, McDonnell TJ, Flowers CR, Vega F, Green MR, Feng L, Kurtz DM, Alizadeh AA, Davis RE, Westin JR. Cherng HJ, et al. Among authors: flowers cr. Blood Adv. 2023 Apr 11;7(7):1137-1145. doi: 10.1182/bloodadvances.2022008174. Blood Adv. 2023. PMID: 36375046 Free PMC article. Clinical Trial.
A polyamine-centric, blood-based metabolite panel predictive of poor response to CAR-T cell therapy in large B cell lymphoma.
Fahrmann JF, Saini NY, Chia-Chi C, Irajizad E, Strati P, Nair R, Fayad LE, Ahmed S, Lee HJ, Iyer S, Steiner R, Vykoukal J, Wu R, Dennison JB, Nastoupil L, Jain P, Wang M, Green M, Westin J, Blumenberg V, Davila M, Champlin R, Shpall EJ, Kebriaei P, Flowers CR, Jain M, Jenq R, Stein-Thoeringer CK, Subklewe M, Neelapu SS, Hanash S. Fahrmann JF, et al. Among authors: flowers cr. Cell Rep Med. 2022 Nov 15;3(11):100720. doi: 10.1016/j.xcrm.2022.100720. Cell Rep Med. 2022. PMID: 36384092 Free PMC article.
Axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma patients in complete metabolic response.
Jallouk AP, Gouni S, Westin J, Feng L, Mistry H, Steiner RE, James J, Noorani M, Horowitz S, Puebla-Osorio N, Fayad LE, Iyer SP, Hawkins M, Flowers CR, Ahmed S, Nastoupil LJ, Kebriaei P, Shpall EJ, Neelapu SS, Nieto Y, Strati P. Jallouk AP, et al. Among authors: flowers cr. Haematologica. 2023 Apr 1;108(4):1163-1167. doi: 10.3324/haematol.2022.281954. Haematologica. 2023. PMID: 36384251 Free PMC article. No abstract available.
A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy.
Stein-Thoeringer CK, Saini NY, Zamir E, Blumenberg V, Schubert ML, Mor U, Fante MA, Schmidt S, Hayase E, Hayase T, Rohrbach R, Chang CC, McDaniel L, Flores I, Gaiser R, Edinger M, Wolff D, Heidenreich M, Strati P, Nair R, Chihara D, Fayad LE, Ahmed S, Iyer SP, Steiner RE, Jain P, Nastoupil LJ, Westin J, Arora R, Wang ML, Turner J, Menges M, Hidalgo-Vargas M, Reid K, Dreger P, Schmitt A, Müller-Tidow C, Locke FL, Davila ML, Champlin RE, Flowers CR, Shpall EJ, Poeck H, Neelapu SS, Schmitt M, Subklewe M, Jain MD, Jenq RR, Elinav E. Stein-Thoeringer CK, et al. Among authors: flowers cr. Nat Med. 2023 Apr;29(4):906-916. doi: 10.1038/s41591-023-02234-6. Epub 2023 Mar 13. Nat Med. 2023. PMID: 36914893 Free PMC article.
PD-L1+ macrophages are associated with favorable features in primary mediastinal (thymic) large B-cell lymphoma.
Steiner RE, Parra ER, Vega F, Feng L, Westin JR, Neelapu SS, Strati P, Green MR, Flowers CR, Solis LM, Wistuba II, Ahmed S, Nair R, Hagemeister FB, Noorani M, Marques-Piubelli ML. Steiner RE, et al. Among authors: flowers cr. Exp Hematol Oncol. 2023 Mar 20;12(1):32. doi: 10.1186/s40164-023-00396-0. Exp Hematol Oncol. 2023. PMID: 36941707 Free PMC article.
Prolonged cytopenia following CD19 CAR T cell therapy is linked with bone marrow infiltration of clonally expanded IFNγ-expressing CD8 T cells.
Strati P, Li X, Deng Q, Marques-Piubelli ML, Henderson J, Watson G, Deaton L, Cain T, Yang H, Ravanmehr V, Fayad LE, Iyer SP, Nastoupil LJ, Hagemeister FB, Parra ER, Saini N, Takahashi K, Fowler NH, Westin JR, Steiner RE, Nair R, Flowers CR, Wang L, Ahmed S, Al-Atrash G, Vega F, Neelapu SS, Green MR. Strati P, et al. Among authors: flowers cr. Cell Rep Med. 2023 Aug 15;4(8):101158. doi: 10.1016/j.xcrm.2023.101158. Cell Rep Med. 2023. PMID: 37586321 Free PMC article.
A single-cell atlas of CD19 chimeric antigen receptor T cells.
Li X, Henderson J, Gordon MJ, Sheikh I, Nastoupil LJ, Westin J, Flowers C, Ahmed S, Wang L, Neelapu SS, Strati P, Deng Q, Green MR. Li X, et al. Cancer Cell. 2023 Nov 13;41(11):1835-1837. doi: 10.1016/j.ccell.2023.08.015. Epub 2023 Sep 21. Cancer Cell. 2023. PMID: 37738975
Real-world analysis of safety and efficacy of CAR T-cell therapy in lymphoma patients with decreased kidney function.
Mamlouk O, Strati P, Feng L, Sun R, Ayers A, Steiner RE, Nair R, Flowers C, Ramdial JL, Saini N, Srour SA, Champlin RE, Kebriaei P, Nastoupil LJ, Rodriguez MA, Shpall EJ, Nieto Y, Westin J, Neelapu SS, Mandayam S, Ahmed S. Mamlouk O, et al. Br J Haematol. 2024 Jan;204(1):e11-e16. doi: 10.1111/bjh.19152. Epub 2023 Oct 11. Br J Haematol. 2024. PMID: 37822075 No abstract available.
396 results