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More than meets the eye in Parkinson's disease and other synucleinopathies: from proteinopathy to lipidopathy.
Acta Neuropathol. 2023 Sep;146(3):369-385. doi: 10.1007/s00401-023-02601-0. Epub 2023 Jul 8.
Acta Neuropathol. 2023.
PMID: 37421475
Free PMC article.
Review.
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells.
Vasili E, Dominguez-Meijide A, Flores-León M, Al-Azzani M, Kanellidi A, Melki R, Stefanis L, Outeiro TF.
Vasili E, et al. Among authors: flores leon m.
Mol Neurobiol. 2022 Feb;59(2):1273-1284. doi: 10.1007/s12035-021-02713-2. Epub 2022 Jan 4.
Mol Neurobiol. 2022.
PMID: 34984585
Free PMC article.
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In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies.
Flores-León M, Lázaro DF, Shvachiy L, Krisko A, Outeiro TF.
Flores-León M, et al.
Biochim Biophys Acta Proteins Proteom. 2021 Oct;1869(10):140693. doi: 10.1016/j.bbapap.2021.140693. Epub 2021 Jul 5.
Biochim Biophys Acta Proteins Proteom. 2021.
PMID: 34237472
Free PMC article.
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Palmitic Acid-Induced NAD+ Depletion is Associated with the Reduced Function of SIRT1 and Increased Expression of BACE1 in Hippocampal Neurons.
Flores-León M, Pérez-Domínguez M, González-Barrios R, Arias C.
Flores-León M, et al.
Neurochem Res. 2019 Jul;44(7):1745-1754. doi: 10.1007/s11064-019-02810-8. Epub 2019 May 9.
Neurochem Res. 2019.
PMID: 31073968
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Transcriptional Profiles Reveal Deregulation of Lipid Metabolism and Inflammatory Pathways in Neurons Exposed to Palmitic Acid.
Flores-León M, Alcaraz N, Pérez-Domínguez M, Torres-Arciga K, Rebollar-Vega R, De la Rosa-Velázquez IA, Arriaga-Canon C, Herrera LA, Arias C, González-Barrios R.
Flores-León M, et al.
Mol Neurobiol. 2021 Sep;58(9):4639-4651. doi: 10.1007/s12035-021-02434-6. Epub 2021 Jun 21.
Mol Neurobiol. 2021.
PMID: 34155583
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PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions.
Sánchez-Alegría K, Flores-León M, Avila-Muñoz E, Rodríguez-Corona N, Arias C.
Sánchez-Alegría K, et al. Among authors: flores leon m.
Int J Mol Sci. 2018 Nov 23;19(12):3725. doi: 10.3390/ijms19123725.
Int J Mol Sci. 2018.
PMID: 30477115
Free PMC article.
Review.
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Role of M4 -receptor cholinergic signaling in direct pathway striatal projection neurons during dopamine depletion.
Vh AR, Ea RO, T HF, M FL, C A, E G, J B.
Vh AR, et al. Among authors: m fl.
Synapse. 2024 Mar;78(2):e22287. doi: 10.1002/syn.22287.
Synapse. 2024.
PMID: 38427384
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Histones and their chaperones: Adaptive remodelers of an ever-changing chromatinic landscape.
Torres-Arciga K, Flores-León M, Ruiz-Pérez S, Trujillo-Pineda M, González-Barrios R, Herrera LA.
Torres-Arciga K, et al. Among authors: flores leon m.
Front Genet. 2022 Nov 16;13:1057846. doi: 10.3389/fgene.2022.1057846. eCollection 2022.
Front Genet. 2022.
PMID: 36468032
Free PMC article.
Review.
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