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101 results

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The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Matthews JM, Qin N, Colburn RW, Dax SL, Hawkins M, McNally JJ, Reany L, Youngman MA, Baker J, Hutchinson T, Liu Y, Lubin ML, Neeper M, Brandt MR, Stone DJ, Flores CM. Matthews JM, et al. Among authors: flores cm. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2922-6. doi: 10.1016/j.bmcl.2012.02.060. Epub 2012 Feb 27. Bioorg Med Chem Lett. 2012. PMID: 22421018
Heteroaryl beta-tetralin ureas as novel antagonists of human TRPV1.
Jetter MC, Youngman MA, McNally JJ, McDonnell ME, Zhang SP, Dubin AE, Nasser N, Codd EE, Flores CM, Dax SL. Jetter MC, et al. Among authors: flores cm. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6160-3. doi: 10.1016/j.bmcl.2007.09.036. Epub 2007 Sep 12. Bioorg Med Chem Lett. 2007. PMID: 17892935
Discovery of piperidine carboxamide TRPV1 antagonists.
Cheung WS, Calvo RR, Tounge BA, Zhang SP, Stone DR, Brandt MR, Hutchinson T, Flores CM, Player MR. Cheung WS, et al. Among authors: flores cm. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4569-72. doi: 10.1016/j.bmcl.2008.07.035. Epub 2008 Jul 15. Bioorg Med Chem Lett. 2008. PMID: 18662879
Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Parks DJ, Parsons WH, Colburn RW, Meegalla SK, Ballentine SK, Illig CR, Qin N, Liu Y, Hutchinson TL, Lubin ML, Stone DJ Jr, Baker JF, Schneider CR, Ma J, Damiano BP, Flores CM, Player MR. Parks DJ, et al. Among authors: flores cm. J Med Chem. 2011 Jan 13;54(1):233-47. doi: 10.1021/jm101075v. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128593
A novel series of pyrazolylpiperidine N-type calcium channel blockers.
Subasinghe NL, Wall MJ, Winters MP, Qin N, Lubin ML, Finley MF, Brandt MR, Neeper MP, Schneider CR, Colburn RW, Flores CM, Sui Z. Subasinghe NL, et al. Among authors: flores cm. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4080-3. doi: 10.1016/j.bmcl.2012.04.075. Epub 2012 May 2. Bioorg Med Chem Lett. 2012. PMID: 22608964
101 results