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Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies.
Perini G, Ciasca G, Minelli E, Papi M, Palmieri V, Maulucci G, Nardini M, Latina V, Corsetti V, Florenzano F, Calissano P, De Spirito M, Amadoro G. Perini G, et al. Among authors: florenzano f. Int J Biol Macromol. 2019 Dec 1;141:278-289. doi: 10.1016/j.ijbiomac.2019.08.220. Epub 2019 Aug 27. Int J Biol Macromol. 2019. PMID: 31470053
Endogenous Aβ causes cell death via early tau hyperphosphorylation.
Amadoro G, Corsetti V, Ciotti MT, Florenzano F, Capsoni S, Amato G, Calissano P. Amadoro G, et al. Among authors: florenzano f. Neurobiol Aging. 2011 Jun;32(6):969-90. doi: 10.1016/j.neurobiolaging.2009.06.005. Epub 2009 Jul 22. Neurobiol Aging. 2011. PMID: 19628305
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.
Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D'Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G. Corsetti V, et al. Among authors: florenzano f. Hum Mol Genet. 2015 Jun 1;24(11):3058-81. doi: 10.1093/hmg/ddv059. Epub 2015 Feb 15. Hum Mol Genet. 2015. PMID: 25687137 Free article.
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies.
Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Maria Sciacca MF, Sinopoli A, Milardi D, Pappalardo G, Marco S, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G. Florenzano F, et al. Oncotarget. 2017 Apr 22;8(39):64745-64778. doi: 10.18632/oncotarget.17371. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029390 Free PMC article.
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
Matrone C, Barbagallo AP, La Rosa LR, Florenzano F, Ciotti MT, Mercanti D, Chao MV, Calissano P, D'Adamio L. Matrone C, et al. Among authors: florenzano f. J Neurosci. 2011 Aug 17;31(33):11756-61. doi: 10.1523/JNEUROSCI.1960-11.2011. J Neurosci. 2011. PMID: 21849536 Free PMC article.
169 results