Fliegert R - Search Results

1

Human dental pulp cells modulate CD8⁺ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro.

Ahmadi P, Yan M, Bauche A, Smeets R, Müller CE, Koch-Nolte F, Haag F, Fliegert R, Kluwe L, Schulze Zur Wiesch J, Hartjen P. Ahmadi P, et al. Among authors: fliegert r. Cell Immunol. 2022 Oct;380:104589. doi: 10.1016/j.cellimm.2022.104589. Epub 2022 Aug 13. Cell Immunol. 2022. PMID: 36084401

2

Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD⁺ Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells.

Baum N, Fliegert R, Bauche A, Hambach J, Menzel S, Haag F, Bannas P, Koch-Nolte F. Baum N, et al. Among authors: fliegert r. Cancers (Basel). 2020 Dec 30;13(1):76. doi: 10.3390/cancers13010076. Cancers (Basel). 2020. PMID: 33396591 Free PMC article.

3

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression.

Schneider E, Winzer R, Rissiek A, Ricklefs I, Meyer-Schwesinger C, Ricklefs FL, Bauche A, Behrends J, Reimer R, Brenna S, Wasielewski H, Lauten M, Rissiek B, Puig B, Cortesi F, Magnus T, Fliegert R, Müller CE, Gagliani N, Tolosa E. Schneider E, et al. Among authors: fliegert r. Nat Commun. 2021 Oct 8;12(1):5911. doi: 10.1038/s41467-021-26134-w. Nat Commun. 2021. PMID: 34625545 Free PMC article.

4

Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

Schwarz N, Drouot L, Nicke A, Fliegert R, Boyer O, Guse AH, Haag F, Adriouch S, Koch-Nolte F. Schwarz N, et al. Among authors: fliegert r. PLoS One. 2012;7(7):e41269. doi: 10.1371/journal.pone.0041269. Epub 2012 Jul 27. PLoS One. 2012. PMID: 22848454 Free PMC article.

5

Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation.

Fliegert R, Heeren J, Koch-Nolte F, Nikolaev VO, Lohr C, Meier C, Guse AH. Fliegert R, et al. Biochem Soc Trans. 2019 Feb 28;47(1):329-337. doi: 10.1042/BST20180419. Epub 2019 Jan 23. Biochem Soc Trans. 2019. PMID: 30674608 Review.

6

P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP.

Johnsen B, Kaschubowski KE, Nader S, Schneider E, Nicola JA, Fliegert R, Wolf IMA, Guse AH, Nikolaev VO, Koch-Nolte F, Haag F. Johnsen B, et al. Among authors: fliegert r. Purinergic Signal. 2019 Jun;15(2):155-166. doi: 10.1007/s11302-019-09654-5. Epub 2019 Apr 23. Purinergic Signal. 2019. PMID: 31016551 Free PMC article.

7

Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells.

Baum N, Eggers M, Koenigsdorf J, Menzel S, Hambach J, Staehler T, Fliegert R, Kulow F, Adam G, Haag F, Bannas P, Koch-Nolte F. Baum N, et al. Among authors: fliegert r. Front Immunol. 2021 Sep 3;12:703574. doi: 10.3389/fimmu.2021.703574. eCollection 2021. Front Immunol. 2021. PMID: 34539634 Free PMC article.

8

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site.

Adriouch S, Bannas P, Schwarz N, Fliegert R, Guse AH, Seman M, Haag F, Koch-Nolte F. Adriouch S, et al. Among authors: fliegert r. FASEB J. 2008 Mar;22(3):861-9. doi: 10.1096/fj.07-9294com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17928361

9

Activation of the P2X7 ion channel by soluble and covalently bound ligands.

Schwarz N, Fliegert R, Adriouch S, Seman M, Guse AH, Haag F, Koch-Nolte F. Schwarz N, et al. Among authors: fliegert r. Purinergic Signal. 2009 Jun;5(2):139-49. doi: 10.1007/s11302-009-9135-5. Epub 2009 Mar 3. Purinergic Signal. 2009. PMID: 19255877 Free PMC article.

10

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.

Gattkowski E, Rutherford TJ, Möckl F, Bauche A, Sander S, Fliegert R, Tidow H. Gattkowski E, et al. Among authors: fliegert r. FEBS J. 2021 Dec;288(23):6769-6782. doi: 10.1111/febs.16097. Epub 2021 Jul 13. FEBS J. 2021. PMID: 34189846 Free PMC article.

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