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Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.
Seneviratne JA, Carter DR, Mittra R, Gifford A, Kim PY, Luo JS, Mayoh C, Salib A, Rahmanto AS, Murray J, Cheng NC, Nagy Z, Wang Q, Kleynhans A, Tan O, Sutton SK, Xue C, Chung SA, Zhang Y, Sun C, Zhang L, Haber M, Norris MD, Fletcher JI, Liu T, Dilda PJ, Hogg PJ, Cheung BB, Marshall GM. Seneviratne JA, et al. Among authors: fletcher ji. Int J Cancer. 2023 Apr 1;152(7):1399-1413. doi: 10.1002/ijc.34349. Epub 2022 Nov 17. Int J Cancer. 2023. PMID: 36346110 Free PMC article.
ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.
Henderson MJ, Haber M, Porro A, Munoz MA, Iraci N, Xue C, Murray J, Flemming CL, Smith J, Fletcher JI, Gherardi S, Kwek CK, Russell AJ, Valli E, London WB, Buxton AB, Ashton LJ, Sartorelli AC, Cohn SL, Schwab M, Marshall GM, Perini G, Norris MD. Henderson MJ, et al. Among authors: fletcher ji. J Natl Cancer Inst. 2011 Aug 17;103(16):1236-51. doi: 10.1093/jnci/djr256. Epub 2011 Jul 28. J Natl Cancer Inst. 2011. PMID: 21799180 Free PMC article.
High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).
Cheung L, Flemming CL, Watt F, Masada N, Yu DM, Huynh T, Conseil G, Tivnan A, Polinsky A, Gudkov AV, Munoz MA, Vishvanath A, Cooper DM, Henderson MJ, Cole SP, Fletcher JI, Haber M, Norris MD. Cheung L, et al. Among authors: fletcher ji. Biochem Pharmacol. 2014 Sep 1;91(1):97-108. doi: 10.1016/j.bcp.2014.05.023. Epub 2014 Jun 25. Biochem Pharmacol. 2014. PMID: 24973542
MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.
O'Brien R, Tran SL, Maritz MF, Liu B, Kong CF, Purgato S, Yang C, Murray J, Russell AJ, Flemming CL, von Jonquieres G, Pickett HA, London WB, Haber M, Gunaratne PH, Norris MD, Perini G, Fletcher JI, MacKenzie KL. O'Brien R, et al. Among authors: fletcher ji. Cancer Res. 2016 Jun 15;76(12):3604-17. doi: 10.1158/0008-5472.CAN-15-0879. Epub 2016 Apr 13. Cancer Res. 2016. PMID: 27197171
63 results