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Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).
Bell M, Foley D, Naylor C, Wood G, Robinson C, Riley J, Epemolu O, Ellis L, Scullion P, Shishikura Y, Osuna-Cabello M, Ferguson L, Pinto E, Fletcher D, Katz E, McLean WHI, Wyatt P, Read KD, Woodland A. Bell M, et al. Among authors: fletcher d. ACS Med Chem Lett. 2019 Feb 14;10(3):341-347. doi: 10.1021/acsmedchemlett.8b00616. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891137 Free PMC article.
Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Varshney D, Petit AP, Bueren-Calabuig JA, Jansen C, Fletcher DA, Peggie M, Weidlich S, Scullion P, Pisliakov AV, Cowling VH. Varshney D, et al. Among authors: fletcher da. Nucleic Acids Res. 2016 Dec 1;44(21):10423-10436. doi: 10.1093/nar/gkw637. Epub 2016 Jul 15. Nucleic Acids Res. 2016. PMID: 27422871 Free PMC article.
Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users.
McKenzie C, Sutcliffe OB, Read KD, Scullion P, Epemolu O, Fletcher D, Helander A, Beck O, Rylski A, Antonides LH, Riley J, Smith SA, Nic Daeid N. McKenzie C, et al. Among authors: fletcher d. Forensic Toxicol. 2018;36(2):359-374. doi: 10.1007/s11419-018-0413-1. Epub 2018 Apr 5. Forensic Toxicol. 2018. PMID: 29963206 Free PMC article.
Substituted Aminoacetamides as Novel Leads for Malaria Treatment.
Norcross NR, Wilson C, Baragaña B, Hallyburton I, Osuna-Cabello M, Norval S, Riley J, Fletcher D, Sinden R, Delves M, Ruecker A, Duffy S, Meister S, Antonova-Koch Y, Crespo B, de Cózar C, Sanz LM, Gamo FJ, Avery VM, Frearson JA, Gray DW, Fairlamb AH, Winzeler EA, Waterson D, Campbell SF, Willis PA, Read KD, Gilbert IH. Norcross NR, et al. Among authors: fletcher d. ChemMedChem. 2019 Jul 17;14(14):1329-1335. doi: 10.1002/cmdc.201900329. Epub 2019 Jul 3. ChemMedChem. 2019. PMID: 31188540 Free PMC article.
Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA.
Prati F, Zuccotto F, Fletcher D, Convery MA, Fernandez-Menendez R, Bates R, Encinas L, Zeng J, Chung CW, De Dios Anton P, Mendoza-Losana A, Mackenzie C, Green SR, Huggett M, Barros D, Wyatt PG, Ray PC. Prati F, et al. Among authors: fletcher d. ChemMedChem. 2018 Apr 6;13(7):672-677. doi: 10.1002/cmdc.201700774. Epub 2018 Feb 19. ChemMedChem. 2018. PMID: 29399991 Free PMC article.
Characterising covalent warhead reactivity.
Martin JS, MacKenzie CJ, Fletcher D, Gilbert IH. Martin JS, et al. Among authors: fletcher d. Bioorg Med Chem. 2019 May 15;27(10):2066-2074. doi: 10.1016/j.bmc.2019.04.002. Epub 2019 Apr 3. Bioorg Med Chem. 2019. PMID: 30975501 Free PMC article.
The metabolism of the synthetic cannabinoids ADB-BUTINACA and ADB-4en-PINACA and their detection in forensic toxicology casework and infused papers seized in prisons.
Kronstrand R, Norman C, Vikingsson S, Biemans A, Valencia Crespo B, Edwards D, Fletcher D, Gilbert N, Persson M, Reid R, Semenova O, Al Teneiji F, Wu X, Dahlén J, NicDaéid N, Tarbah F, Sutcliffe OB, McKenzie C, Gréen H. Kronstrand R, et al. Among authors: fletcher d. Drug Test Anal. 2022 Apr;14(4):634-652. doi: 10.1002/dta.3203. Epub 2021 Dec 10. Drug Test Anal. 2022. PMID: 34811926 Free article.
2024 RECOVER CPR Guidelines.
Burkitt-Creedon JM, Boller M, Fletcher DJ. Burkitt-Creedon JM, et al. Among authors: fletcher dj. J Vet Emerg Crit Care (San Antonio). 2024 May 10. doi: 10.1111/vec.13382. Online ahead of print. J Vet Emerg Crit Care (San Antonio). 2024. PMID: 38728061 Estonian. No abstract available.
1,183 results